Central Pain and Complex Motoric Symptoms after Gosarelin Therapy of Prostate Cancer

A 76-year-old man with prostate cancer T3N0M0 and increasing PSA was treated with goserelin three times in a half year. As soon as the first treatment, he described subjective muscle weakness. After the third treatment, he developed complex motoric symptoms and atypical central pain with a likely as...

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Main Authors: G. Ernst, A. Gericke, P. Berg
Format: Article
Language:English
Published: Wiley 2004-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2004.197
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author G. Ernst
A. Gericke
P. Berg
author_facet G. Ernst
A. Gericke
P. Berg
author_sort G. Ernst
collection DOAJ
description A 76-year-old man with prostate cancer T3N0M0 and increasing PSA was treated with goserelin three times in a half year. As soon as the first treatment, he described subjective muscle weakness. After the third treatment, he developed complex motoric symptoms and atypical central pain with a likely association to goserelin. His left arm had signs of spastic movement; pain deteriorated after relaxation. The right hand showed muscle cramps under passive movements of the left arm that were not typical for rigor. He felt aching and partial burning pain in his whole body. There were few allodynic areas, mainly in the left arm. Several treatment approaches failed and the patient died some weeks after the first contact with our pain clinic due to pneumonia.
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spelling doaj-art-21ef51220d9e41868aa9d73820c414372025-02-03T06:00:39ZengWileyThe Scientific World Journal1537-744X2004-01-01496997310.1100/tsw.2004.197Central Pain and Complex Motoric Symptoms after Gosarelin Therapy of Prostate CancerG. Ernst0A. Gericke1P. Berg2Blefjell sykehus Kongsberg, Anestesi, Drammensvei 4, 3612 Kongsberg, NorwayTelegrafen Legekontor Myntgt 4 3612 Kongsberg, NorwayBlefjell sykehus Kongsberg, Anestesi, Drammensvei 4, 3612 Kongsberg, NorwayA 76-year-old man with prostate cancer T3N0M0 and increasing PSA was treated with goserelin three times in a half year. As soon as the first treatment, he described subjective muscle weakness. After the third treatment, he developed complex motoric symptoms and atypical central pain with a likely association to goserelin. His left arm had signs of spastic movement; pain deteriorated after relaxation. The right hand showed muscle cramps under passive movements of the left arm that were not typical for rigor. He felt aching and partial burning pain in his whole body. There were few allodynic areas, mainly in the left arm. Several treatment approaches failed and the patient died some weeks after the first contact with our pain clinic due to pneumonia.http://dx.doi.org/10.1100/tsw.2004.197
spellingShingle G. Ernst
A. Gericke
P. Berg
Central Pain and Complex Motoric Symptoms after Gosarelin Therapy of Prostate Cancer
The Scientific World Journal
title Central Pain and Complex Motoric Symptoms after Gosarelin Therapy of Prostate Cancer
title_full Central Pain and Complex Motoric Symptoms after Gosarelin Therapy of Prostate Cancer
title_fullStr Central Pain and Complex Motoric Symptoms after Gosarelin Therapy of Prostate Cancer
title_full_unstemmed Central Pain and Complex Motoric Symptoms after Gosarelin Therapy of Prostate Cancer
title_short Central Pain and Complex Motoric Symptoms after Gosarelin Therapy of Prostate Cancer
title_sort central pain and complex motoric symptoms after gosarelin therapy of prostate cancer
url http://dx.doi.org/10.1100/tsw.2004.197
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