The impact of antibiotic use on outcomes of relapsed/refractory multiple myeloma patients treated with CAR-T therapy

The impact of antibiotic use on outcomes of relapsed/refractory multiple myeloma patients treated with CAR-T therapy

BackgroundIn recent years, chimeric antigen receptor (CAR)-T cell therapy has achieved tremendous efficacy in relapsed/refractory multiple myeloma (R/R MM). However, the impact of antibiotic (ATB) use on R/R MM patients treated with CAR-T is still not known. The aim of our study was to analyse the i...

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Main Authors: Lingling Yin, Bin Lv, Jiao Ge, Yuekun Qi, Jieyun Xia, Sha Ma, Ying Wang, Yang Liu, Dian Zhou, Jiang Cao, Zhiling Yan, Kunming Qi, Wei Sang, Depeng Li, Hai Cheng, Wei Chen, Kailin Xu, Weiying Gu, Zhenyu Li, Feng Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
Subjects:
chimeric antigen receptor T cell
antibiotic
relapsed/refractory
multiple myeloma
outcome
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1566016/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1566016/full

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