Women’s preferences for testing to predict breast cancer risk – a discrete choice experiment
Abstract Background Risk-based breast cancer screening offers a more targeted and potentially cost-effective approach in cancer detection compared to age-based screening. This study aims to understand women’s preferences and willingness for undergoing risk assessment tests. Methods A discrete choice...
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| Language: | English |
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BMC
2025-01-01
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| Series: | Journal of Translational Medicine |
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| Online Access: | https://doi.org/10.1186/s12967-025-06119-9 |
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| author | Yi Wang Peh Joo Ho Langming Mou Jingmei Li |
| author_facet | Yi Wang Peh Joo Ho Langming Mou Jingmei Li |
| author_sort | Yi Wang |
| collection | DOAJ |
| description | Abstract Background Risk-based breast cancer screening offers a more targeted and potentially cost-effective approach in cancer detection compared to age-based screening. This study aims to understand women’s preferences and willingness for undergoing risk assessment tests. Methods A discrete choice experiment (DCE) was conducted. Six attributes were selected to construct the DCE questionnaire: one-time cost of the test, methods for reducing late-stage breast cancer, annual breast cancer screening expenses, insurance coverage for early-stage breast cancer, family risk correlation, and risk communication methods. Women aged between 21 and 59 were recruited from Singapore. Latent class analysis was performed. Results Three hundred twenty-eight women were included in the analysis and classified into two classes: test supporters and non-supporters. Both classes prioritised test costs and screening costs. Among non-cost attributes, the potential to reduce late-stage breast cancer diagnosis was the most influential factor. Insurance coverage increased willingness to undergo testing. Risk communication methods were not significant in influencing the decision of undergoing tests. Non-supporters were less inclined to take the test if family risk correlation was high. Younger women, married women, full-time employees, and those with a history of breast disease were more likely to be supporters. Women with a family history of breast cancer were more likely to be non-supporters. Conclusions Financial incentives play a notable role in increasing the uptake of risk-prediction tests. However, the programme’s success depends on understanding and addressing the diverse preferences of women. While cost considerations ranked highly, additional strategies are needed to engage groups that are hesitant, particularly those with a high family risk correlation. |
| format | Article |
| id | doaj-art-21d83b4dd5d043078634a93ea2ddb805 |
| institution | Kabale University |
| issn | 1479-5876 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Translational Medicine |
| spelling | doaj-art-21d83b4dd5d043078634a93ea2ddb8052025-01-26T12:50:08ZengBMCJournal of Translational Medicine1479-58762025-01-0123111110.1186/s12967-025-06119-9Women’s preferences for testing to predict breast cancer risk – a discrete choice experimentYi Wang0Peh Joo Ho1Langming Mou2Jingmei Li3Saw Swee Hock School of Public Health, National University of Singapore and National University Health SystemSaw Swee Hock School of Public Health, National University of Singapore and National University Health SystemSaw Swee Hock School of Public Health, National University of Singapore and National University Health SystemGenome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR)Abstract Background Risk-based breast cancer screening offers a more targeted and potentially cost-effective approach in cancer detection compared to age-based screening. This study aims to understand women’s preferences and willingness for undergoing risk assessment tests. Methods A discrete choice experiment (DCE) was conducted. Six attributes were selected to construct the DCE questionnaire: one-time cost of the test, methods for reducing late-stage breast cancer, annual breast cancer screening expenses, insurance coverage for early-stage breast cancer, family risk correlation, and risk communication methods. Women aged between 21 and 59 were recruited from Singapore. Latent class analysis was performed. Results Three hundred twenty-eight women were included in the analysis and classified into two classes: test supporters and non-supporters. Both classes prioritised test costs and screening costs. Among non-cost attributes, the potential to reduce late-stage breast cancer diagnosis was the most influential factor. Insurance coverage increased willingness to undergo testing. Risk communication methods were not significant in influencing the decision of undergoing tests. Non-supporters were less inclined to take the test if family risk correlation was high. Younger women, married women, full-time employees, and those with a history of breast disease were more likely to be supporters. Women with a family history of breast cancer were more likely to be non-supporters. Conclusions Financial incentives play a notable role in increasing the uptake of risk-prediction tests. However, the programme’s success depends on understanding and addressing the diverse preferences of women. While cost considerations ranked highly, additional strategies are needed to engage groups that are hesitant, particularly those with a high family risk correlation.https://doi.org/10.1186/s12967-025-06119-9AsianHeterogenous populationRisk-based screeningPolygenic risk scorePRSAdherence |
| spellingShingle | Yi Wang Peh Joo Ho Langming Mou Jingmei Li Women’s preferences for testing to predict breast cancer risk – a discrete choice experiment Journal of Translational Medicine Asian Heterogenous population Risk-based screening Polygenic risk score PRS Adherence |
| title | Women’s preferences for testing to predict breast cancer risk – a discrete choice experiment |
| title_full | Women’s preferences for testing to predict breast cancer risk – a discrete choice experiment |
| title_fullStr | Women’s preferences for testing to predict breast cancer risk – a discrete choice experiment |
| title_full_unstemmed | Women’s preferences for testing to predict breast cancer risk – a discrete choice experiment |
| title_short | Women’s preferences for testing to predict breast cancer risk – a discrete choice experiment |
| title_sort | women s preferences for testing to predict breast cancer risk a discrete choice experiment |
| topic | Asian Heterogenous population Risk-based screening Polygenic risk score PRS Adherence |
| url | https://doi.org/10.1186/s12967-025-06119-9 |
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