Research Progress on the Mechanism of Acupuncture Treatment for Nonalcoholic Fatty Liver Disease

Nonalcoholic fatty liver disease (NAFLD) represents the most common chronic liver disease worldwide, ranging from simple steatosis and nonalcoholic steatohepatitis to fibrosis, cirrhosis, and hepatocellular carcinoma. Acupuncture is a long-established treatment in traditional Chinese medicine. In re...

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Main Authors: Bai Li, Li Fang
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2022/5259088
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author Bai Li
Li Fang
author_facet Bai Li
Li Fang
author_sort Bai Li
collection DOAJ
description Nonalcoholic fatty liver disease (NAFLD) represents the most common chronic liver disease worldwide, ranging from simple steatosis and nonalcoholic steatohepatitis to fibrosis, cirrhosis, and hepatocellular carcinoma. Acupuncture is a long-established treatment in traditional Chinese medicine. In recent years, increasing evidence has pointed to the effectiveness of acupuncture in the treatment of NAFLD, and a certain degree of progress has been made in the study of related mechanisms. However, previous systematic reviews have not discussed the characteristics and the related mechanisms of acupuncture in the treatment of NAFLD. Therefore, this review synthesizes the progress in research on acupuncture in the context of NAFLD treatment by the inhibition of inflammatory responses, regulation of lipid metabolism disorder, treatment of insulin resistance, antagonization of oxidative stress injury, and interference with endoplasmic reticulum stress. Overall, we sought to highlight the latest research results, potential applications, and ongoing challenges of this therapy.
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series Gastroenterology Research and Practice
spelling doaj-art-21c763d4d5ba4f369fe507f6623b0dac2025-02-03T01:32:35ZengWileyGastroenterology Research and Practice1687-630X2022-01-01202210.1155/2022/5259088Research Progress on the Mechanism of Acupuncture Treatment for Nonalcoholic Fatty Liver DiseaseBai Li0Li Fang1The Acumox and Tuina CollegeThe Acumox and Tuina CollegeNonalcoholic fatty liver disease (NAFLD) represents the most common chronic liver disease worldwide, ranging from simple steatosis and nonalcoholic steatohepatitis to fibrosis, cirrhosis, and hepatocellular carcinoma. Acupuncture is a long-established treatment in traditional Chinese medicine. In recent years, increasing evidence has pointed to the effectiveness of acupuncture in the treatment of NAFLD, and a certain degree of progress has been made in the study of related mechanisms. However, previous systematic reviews have not discussed the characteristics and the related mechanisms of acupuncture in the treatment of NAFLD. Therefore, this review synthesizes the progress in research on acupuncture in the context of NAFLD treatment by the inhibition of inflammatory responses, regulation of lipid metabolism disorder, treatment of insulin resistance, antagonization of oxidative stress injury, and interference with endoplasmic reticulum stress. Overall, we sought to highlight the latest research results, potential applications, and ongoing challenges of this therapy.http://dx.doi.org/10.1155/2022/5259088
spellingShingle Bai Li
Li Fang
Research Progress on the Mechanism of Acupuncture Treatment for Nonalcoholic Fatty Liver Disease
Gastroenterology Research and Practice
title Research Progress on the Mechanism of Acupuncture Treatment for Nonalcoholic Fatty Liver Disease
title_full Research Progress on the Mechanism of Acupuncture Treatment for Nonalcoholic Fatty Liver Disease
title_fullStr Research Progress on the Mechanism of Acupuncture Treatment for Nonalcoholic Fatty Liver Disease
title_full_unstemmed Research Progress on the Mechanism of Acupuncture Treatment for Nonalcoholic Fatty Liver Disease
title_short Research Progress on the Mechanism of Acupuncture Treatment for Nonalcoholic Fatty Liver Disease
title_sort research progress on the mechanism of acupuncture treatment for nonalcoholic fatty liver disease
url http://dx.doi.org/10.1155/2022/5259088
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AT lifang researchprogressonthemechanismofacupuncturetreatmentfornonalcoholicfattyliverdisease