A unique case report on campylobacter rectus infection leading to acute motor axonal neuropathy in a pediatric patient
A unique case report on campylobacter rectus infection leading to acute motor axonal neuropathy in a pediatric patient. Campylobacter rectus is an anaerobic bacterium found in the oral cavity. While it has been linked to periodontal disease, its association with acute motor axonal neuropathy (AMAN),...
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Elsevier
2025-03-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043324013359 |
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| author | Uchechukwu Ibewuike, MBBS John Kim, MD Swati Mody, MBBS Gregory Obala, MD Ebere Ibezim, MBBS |
| author_facet | Uchechukwu Ibewuike, MBBS John Kim, MD Swati Mody, MBBS Gregory Obala, MD Ebere Ibezim, MBBS |
| author_sort | Uchechukwu Ibewuike, MBBS |
| collection | DOAJ |
| description | A unique case report on campylobacter rectus infection leading to acute motor axonal neuropathy in a pediatric patient. Campylobacter rectus is an anaerobic bacterium found in the oral cavity. While it has been linked to periodontal disease, its association with acute motor axonal neuropathy (AMAN), a variant of Guillain-Barre Syndrome, remains unverified. The majority of Guillain-Barre Syndrome (GBS) cases related to Campylobacter are attributed to the species Campylobacter jejuni. A 14-year-old male was admitted to the hospital with sepsis. About 1 week before his admission, the patient sustained an injury to his left eye from a cell phone, resulting in considerable edema. A punch biopsy of the left periorbital soft tissue yielded a culture positive for Campylobacter rectus. Following this, the patient developed weakness in all 4 limbs, with more pronounced weakness in the legs than in the arms, and he lost motor function in both lower legs, although sensory function remained intact. Analysis of cerebrospinal fluid (CSF) revealed albuminocytologic dissociation. An MRI of the spine showed anterior nerve root predominant enhancement.Electromyography was consistent with acute motor axonal neuropathy. Acute motor axonal neuropathy (AMAN), a subtype of Guillain-Barré Syndrome, arises from an atypical immune response, frequently initiated by infections caused by Campylobacter jejuni, although other infectious agents have also been identified. To the best of our knowledge, this is the first recorded instance associating Campylobacter rectus infection with AMAN. |
| format | Article |
| id | doaj-art-2181957eaeb84643926e785ae8efd623 |
| institution | Kabale University |
| issn | 1930-0433 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj-art-2181957eaeb84643926e785ae8efd6232025-01-18T05:03:58ZengElsevierRadiology Case Reports1930-04332025-03-0120314821485A unique case report on campylobacter rectus infection leading to acute motor axonal neuropathy in a pediatric patientUchechukwu Ibewuike, MBBS0John Kim, MD1Swati Mody, MBBS2Gregory Obala, MD3Ebere Ibezim, MBBS4Division of Neuroradiology/NIR, University of Michigan, MI, USA; Corresponding author.Division of Neuroradiology/NIR, University of Michigan, MI, USADivision of Pediatric Radiology, University of Michigan, MI, USASection of Neuroradiology, Oregon Health and Science University, Portland, OR, USADepartment of Radiology, Imo State University, Imo State, NigeriaA unique case report on campylobacter rectus infection leading to acute motor axonal neuropathy in a pediatric patient. Campylobacter rectus is an anaerobic bacterium found in the oral cavity. While it has been linked to periodontal disease, its association with acute motor axonal neuropathy (AMAN), a variant of Guillain-Barre Syndrome, remains unverified. The majority of Guillain-Barre Syndrome (GBS) cases related to Campylobacter are attributed to the species Campylobacter jejuni. A 14-year-old male was admitted to the hospital with sepsis. About 1 week before his admission, the patient sustained an injury to his left eye from a cell phone, resulting in considerable edema. A punch biopsy of the left periorbital soft tissue yielded a culture positive for Campylobacter rectus. Following this, the patient developed weakness in all 4 limbs, with more pronounced weakness in the legs than in the arms, and he lost motor function in both lower legs, although sensory function remained intact. Analysis of cerebrospinal fluid (CSF) revealed albuminocytologic dissociation. An MRI of the spine showed anterior nerve root predominant enhancement.Electromyography was consistent with acute motor axonal neuropathy. Acute motor axonal neuropathy (AMAN), a subtype of Guillain-Barré Syndrome, arises from an atypical immune response, frequently initiated by infections caused by Campylobacter jejuni, although other infectious agents have also been identified. To the best of our knowledge, this is the first recorded instance associating Campylobacter rectus infection with AMAN.http://www.sciencedirect.com/science/article/pii/S1930043324013359Acute motor axonal neuropathyGuillain-barre syndromeCampylobacter rectus |
| spellingShingle | Uchechukwu Ibewuike, MBBS John Kim, MD Swati Mody, MBBS Gregory Obala, MD Ebere Ibezim, MBBS A unique case report on campylobacter rectus infection leading to acute motor axonal neuropathy in a pediatric patient Radiology Case Reports Acute motor axonal neuropathy Guillain-barre syndrome Campylobacter rectus |
| title | A unique case report on campylobacter rectus infection leading to acute motor axonal neuropathy in a pediatric patient |
| title_full | A unique case report on campylobacter rectus infection leading to acute motor axonal neuropathy in a pediatric patient |
| title_fullStr | A unique case report on campylobacter rectus infection leading to acute motor axonal neuropathy in a pediatric patient |
| title_full_unstemmed | A unique case report on campylobacter rectus infection leading to acute motor axonal neuropathy in a pediatric patient |
| title_short | A unique case report on campylobacter rectus infection leading to acute motor axonal neuropathy in a pediatric patient |
| title_sort | unique case report on campylobacter rectus infection leading to acute motor axonal neuropathy in a pediatric patient |
| topic | Acute motor axonal neuropathy Guillain-barre syndrome Campylobacter rectus |
| url | http://www.sciencedirect.com/science/article/pii/S1930043324013359 |
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