Exacerbation of diabetes due to F. Nucleatum LPS-induced SGLT2 overexpression in the renal proximal tubular epithelial cells

Exacerbation of diabetes due to F. Nucleatum LPS-induced SGLT2 overexpression in the renal proximal tubular epithelial cells

Abstract Background Diabetes treatments by the control of sodium-glucose cotransporter 2 (SGLT2) is commonly conducted while there are still uncertainties about the mechanisms for the SGLT2 overexpression in kidneys with diabetes. Previously, we have reported that glomeruli and proximal tubules with...

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Bibliographic Details
Main Authors: Aiko Seki, Koichiro Kajiwara, Jumpei Teramachi, Masahiko Egusa, Takuya Miyawaki, Yoshihiko Sawa
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Nephrology
Subjects:
F. Nucleatum
Diabetic exacerbation
Diabetic nephropathy
SGLT2
Online Access:https://doi.org/10.1186/s12882-025-03965-z
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