A Case of Granulomatosis with Polyangiitis with Various Breast Lesions as the Initial Symptoms: A Case-Based Review
A 44-year-old woman presenting with pus-like discharge from the nipples visited our hospital for scleritis. Subcutaneous induration and ulceration were found on her breast. She was diagnosed with granulomatosis with polyangiitis (GPA) considering scleritis, sinusitis, cutaneous granuloma formation,...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Rheumatology |
| Online Access: | http://dx.doi.org/10.1155/2021/4416072 |
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| _version_ | 1832560584013381632 |
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| author | Masatoshi Kawataka Toshiki Kido Reina Tsuda Takafumi Onose Ryoko Asano Miho Yamazaki Naonori Sugishita Hiroyuki Hounoki Toshiko Kakiuchi Koichiro Shinoda Kazuyuki Tobe |
| author_facet | Masatoshi Kawataka Toshiki Kido Reina Tsuda Takafumi Onose Ryoko Asano Miho Yamazaki Naonori Sugishita Hiroyuki Hounoki Toshiko Kakiuchi Koichiro Shinoda Kazuyuki Tobe |
| author_sort | Masatoshi Kawataka |
| collection | DOAJ |
| description | A 44-year-old woman presenting with pus-like discharge from the nipples visited our hospital for scleritis. Subcutaneous induration and ulceration were found on her breast. She was diagnosed with granulomatosis with polyangiitis (GPA) considering scleritis, sinusitis, cutaneous granuloma formation, and antiproteinase 3-antineutrophil cytoplasmic antibodies and was successfully treated with glucocorticoids. Fifteen months later, she developed pulmonary consolidation and a right breast nodule. Biopsies of the breast nodule showed granulomatous vasculitis, and she was treated with rituximab. While breast involvement in GPA is rare, unilateral breast mass is a typical clinical feature; thus, GPA should be considered in such cases. |
| format | Article |
| id | doaj-art-215f68adc6394738a1386fa6e92a0a51 |
| institution | Kabale University |
| issn | 2090-6889 2090-6897 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Rheumatology |
| spelling | doaj-art-215f68adc6394738a1386fa6e92a0a512025-02-03T01:27:06ZengWileyCase Reports in Rheumatology2090-68892090-68972021-01-01202110.1155/2021/44160724416072A Case of Granulomatosis with Polyangiitis with Various Breast Lesions as the Initial Symptoms: A Case-Based ReviewMasatoshi Kawataka0Toshiki Kido1Reina Tsuda2Takafumi Onose3Ryoko Asano4Miho Yamazaki5Naonori Sugishita6Hiroyuki Hounoki7Toshiko Kakiuchi8Koichiro Shinoda9Kazuyuki Tobe10First Department of Internal Medicine, University of Toyama, Toyama, JapanFirst Department of Internal Medicine, University of Toyama, Toyama, JapanFirst Department of Internal Medicine, University of Toyama, Toyama, JapanFirst Department of Internal Medicine, University of Toyama, Toyama, JapanFirst Department of Internal Medicine, University of Toyama, Toyama, JapanFirst Department of Internal Medicine, University of Toyama, Toyama, JapanFirst Department of Internal Medicine, University of Toyama, Toyama, JapanFirst Department of Internal Medicine, University of Toyama, Toyama, JapanDepartment of Diagnostic Pathology, University of Toyama, Toyama, JapanFirst Department of Internal Medicine, University of Toyama, Toyama, JapanFirst Department of Internal Medicine, University of Toyama, Toyama, JapanA 44-year-old woman presenting with pus-like discharge from the nipples visited our hospital for scleritis. Subcutaneous induration and ulceration were found on her breast. She was diagnosed with granulomatosis with polyangiitis (GPA) considering scleritis, sinusitis, cutaneous granuloma formation, and antiproteinase 3-antineutrophil cytoplasmic antibodies and was successfully treated with glucocorticoids. Fifteen months later, she developed pulmonary consolidation and a right breast nodule. Biopsies of the breast nodule showed granulomatous vasculitis, and she was treated with rituximab. While breast involvement in GPA is rare, unilateral breast mass is a typical clinical feature; thus, GPA should be considered in such cases.http://dx.doi.org/10.1155/2021/4416072 |
| spellingShingle | Masatoshi Kawataka Toshiki Kido Reina Tsuda Takafumi Onose Ryoko Asano Miho Yamazaki Naonori Sugishita Hiroyuki Hounoki Toshiko Kakiuchi Koichiro Shinoda Kazuyuki Tobe A Case of Granulomatosis with Polyangiitis with Various Breast Lesions as the Initial Symptoms: A Case-Based Review Case Reports in Rheumatology |
| title | A Case of Granulomatosis with Polyangiitis with Various Breast Lesions as the Initial Symptoms: A Case-Based Review |
| title_full | A Case of Granulomatosis with Polyangiitis with Various Breast Lesions as the Initial Symptoms: A Case-Based Review |
| title_fullStr | A Case of Granulomatosis with Polyangiitis with Various Breast Lesions as the Initial Symptoms: A Case-Based Review |
| title_full_unstemmed | A Case of Granulomatosis with Polyangiitis with Various Breast Lesions as the Initial Symptoms: A Case-Based Review |
| title_short | A Case of Granulomatosis with Polyangiitis with Various Breast Lesions as the Initial Symptoms: A Case-Based Review |
| title_sort | case of granulomatosis with polyangiitis with various breast lesions as the initial symptoms a case based review |
| url | http://dx.doi.org/10.1155/2021/4416072 |
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