Exploring The Influence Of Vitamin D In The Management Of Acne Vulgaris: A Pilot Study
Objective: The study aimed to explore the potential benefits of vitamin D supplementation in improving acne severity. Methods: This pilot study was carried out at HIT Hospital, Taxila. The study included nine female patients aged between 12 and 30 years, with acne vulgaris and having deficient se...
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Rawalpindi Medical University
2023-12-01
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| Series: | Journal of Rawalpindi Medical College |
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| Online Access: | https://www.journalrmc.com/index.php/JRMC/article/view/2364 |
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| author | Aqsa Naheed Aashi Mughal Tehzeeb Zehra Rahila Aamir Samina Fida Taha Naveed |
| author_facet | Aqsa Naheed Aashi Mughal Tehzeeb Zehra Rahila Aamir Samina Fida Taha Naveed |
| author_sort | Aqsa Naheed |
| collection | DOAJ |
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Objective: The study aimed to explore the potential benefits of vitamin D supplementation in improving acne severity.
Methods: This pilot study was carried out at HIT Hospital, Taxila. The study included nine female patients aged between 12 and 30 years, with acne vulgaris and having deficient serum 25-hydroxyvitamin D3 (25(OH)D) levels (<30 nmol/L). Exclusion criteria included the use of topical or oral treatments for acne, including retinoids, as well as those with a history of multivitamin or systemic steroid intake, and patients with any chronic disease. Global Acne Grading (GAG) score was used to assess the severity of acne vulgaris. Patients received a daily dosage of 1000 IU of vitamin D drops per day for 2 months so that vitamin D deficiency is corrected. After 2 months, the GAG score was re-calculated and documented. Data analysis was performed using SPSS version 28.
Results: The mean age of the study participants was 18.33 years (SD= 3.3 Years). A statistically insignificant association (p=0.49) and weak positive correlation (r= 0.17, p=0.65) were observed between Vit D levels and acne Status and GAG-1 score on applying chi-square test and Pearson correlation respectively. A paired-sample t-test showed a significant difference in the GAG-1 Score (Mean=25.44, SD=7.6) and GAG-2 Score (M=15.1, SD=4.5) after Vit D supplementation. t (5.3), (p= 0.001).
Conclusion: The results suggest that correcting vitamin D deficiency through supplementation resulted in a significant improvement in acne severity.
Keywords: Acne vulgaris, Vitamin D, GAG score
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| format | Article |
| id | doaj-art-211df1a9a45342db95f9130981776f0b |
| institution | Kabale University |
| issn | 1683-3562 1683-3570 |
| language | English |
| publishDate | 2023-12-01 |
| publisher | Rawalpindi Medical University |
| record_format | Article |
| series | Journal of Rawalpindi Medical College |
| spelling | doaj-art-211df1a9a45342db95f9130981776f0b2025-02-06T08:40:32ZengRawalpindi Medical UniversityJournal of Rawalpindi Medical College1683-35621683-35702023-12-0127410.37939/jrmc.v27i4.2364Exploring The Influence Of Vitamin D In The Management Of Acne Vulgaris: A Pilot Study Aqsa Naheed0Aashi Mughal1Tehzeeb Zehra2Rahila Aamir3Samina FidaTaha NaveedHITEC-IMS, TaxillaHITEC-IMSShifa Tameer-e-Millat University, IslamabadShifa Tameer-e-Millat University, Islamabad Objective: The study aimed to explore the potential benefits of vitamin D supplementation in improving acne severity. Methods: This pilot study was carried out at HIT Hospital, Taxila. The study included nine female patients aged between 12 and 30 years, with acne vulgaris and having deficient serum 25-hydroxyvitamin D3 (25(OH)D) levels (<30 nmol/L). Exclusion criteria included the use of topical or oral treatments for acne, including retinoids, as well as those with a history of multivitamin or systemic steroid intake, and patients with any chronic disease. Global Acne Grading (GAG) score was used to assess the severity of acne vulgaris. Patients received a daily dosage of 1000 IU of vitamin D drops per day for 2 months so that vitamin D deficiency is corrected. After 2 months, the GAG score was re-calculated and documented. Data analysis was performed using SPSS version 28. Results: The mean age of the study participants was 18.33 years (SD= 3.3 Years). A statistically insignificant association (p=0.49) and weak positive correlation (r= 0.17, p=0.65) were observed between Vit D levels and acne Status and GAG-1 score on applying chi-square test and Pearson correlation respectively. A paired-sample t-test showed a significant difference in the GAG-1 Score (Mean=25.44, SD=7.6) and GAG-2 Score (M=15.1, SD=4.5) after Vit D supplementation. t (5.3), (p= 0.001). Conclusion: The results suggest that correcting vitamin D deficiency through supplementation resulted in a significant improvement in acne severity. Keywords: Acne vulgaris, Vitamin D, GAG score https://www.journalrmc.com/index.php/JRMC/article/view/2364Acne vulgaris, Vitamin D, GAG score |
| spellingShingle | Aqsa Naheed Aashi Mughal Tehzeeb Zehra Rahila Aamir Samina Fida Taha Naveed Exploring The Influence Of Vitamin D In The Management Of Acne Vulgaris: A Pilot Study Journal of Rawalpindi Medical College Acne vulgaris, Vitamin D, GAG score |
| title | Exploring The Influence Of Vitamin D In The Management Of Acne Vulgaris: A Pilot Study |
| title_full | Exploring The Influence Of Vitamin D In The Management Of Acne Vulgaris: A Pilot Study |
| title_fullStr | Exploring The Influence Of Vitamin D In The Management Of Acne Vulgaris: A Pilot Study |
| title_full_unstemmed | Exploring The Influence Of Vitamin D In The Management Of Acne Vulgaris: A Pilot Study |
| title_short | Exploring The Influence Of Vitamin D In The Management Of Acne Vulgaris: A Pilot Study |
| title_sort | exploring the influence of vitamin d in the management of acne vulgaris a pilot study |
| topic | Acne vulgaris, Vitamin D, GAG score |
| url | https://www.journalrmc.com/index.php/JRMC/article/view/2364 |
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