Iron Deficiency Anemia: Focus on Infectious Diseases in Lesser Developed Countries

Iron deficiency anemia is thought to affect the health of more than one billion people worldwide, with the greatest burden of disease experienced in lesser developed countries, particularly women of reproductive age and children. This greater disease burden is due to both nutritional and infectious...

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Main Authors: Julia G. Shaw, Jennifer F. Friedman
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Anemia
Online Access:http://dx.doi.org/10.1155/2011/260380
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author Julia G. Shaw
Jennifer F. Friedman
author_facet Julia G. Shaw
Jennifer F. Friedman
author_sort Julia G. Shaw
collection DOAJ
description Iron deficiency anemia is thought to affect the health of more than one billion people worldwide, with the greatest burden of disease experienced in lesser developed countries, particularly women of reproductive age and children. This greater disease burden is due to both nutritional and infectious etiologies. Individuals in lesser developed countries have diets that are much lower in iron, less access to multivitamins for young children and pregnant women, and increased rates of fertility which increase demands for iron through the life course. Infectious diseases, particularly parasitic diseases, also lead to both extracorporeal iron loss and anemia of inflammation, which decreases bioavailability of iron to host tissues. This paper will address the unique etiologies and consequences of both iron deficiency anemia and the alterations in iron absorption and distribution seen in the context of anemia of inflammation. Implications for diagnosis and treatment in this unique context will also be discussed.
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spelling doaj-art-20f1701a23954cf9985bfec5bc67a63f2025-02-03T00:59:21ZengWileyAnemia2090-12672090-12752011-01-01201110.1155/2011/260380260380Iron Deficiency Anemia: Focus on Infectious Diseases in Lesser Developed CountriesJulia G. Shaw0Jennifer F. Friedman1Public Health Program, Division of Biology and Medicine, Brown University, Providence, RI 02912, USALifespan Hospital Center for International Health Research, 55 Claverick Street, Suite 100, Providence, RI 02903, USAIron deficiency anemia is thought to affect the health of more than one billion people worldwide, with the greatest burden of disease experienced in lesser developed countries, particularly women of reproductive age and children. This greater disease burden is due to both nutritional and infectious etiologies. Individuals in lesser developed countries have diets that are much lower in iron, less access to multivitamins for young children and pregnant women, and increased rates of fertility which increase demands for iron through the life course. Infectious diseases, particularly parasitic diseases, also lead to both extracorporeal iron loss and anemia of inflammation, which decreases bioavailability of iron to host tissues. This paper will address the unique etiologies and consequences of both iron deficiency anemia and the alterations in iron absorption and distribution seen in the context of anemia of inflammation. Implications for diagnosis and treatment in this unique context will also be discussed.http://dx.doi.org/10.1155/2011/260380
spellingShingle Julia G. Shaw
Jennifer F. Friedman
Iron Deficiency Anemia: Focus on Infectious Diseases in Lesser Developed Countries
Anemia
title Iron Deficiency Anemia: Focus on Infectious Diseases in Lesser Developed Countries
title_full Iron Deficiency Anemia: Focus on Infectious Diseases in Lesser Developed Countries
title_fullStr Iron Deficiency Anemia: Focus on Infectious Diseases in Lesser Developed Countries
title_full_unstemmed Iron Deficiency Anemia: Focus on Infectious Diseases in Lesser Developed Countries
title_short Iron Deficiency Anemia: Focus on Infectious Diseases in Lesser Developed Countries
title_sort iron deficiency anemia focus on infectious diseases in lesser developed countries
url http://dx.doi.org/10.1155/2011/260380
work_keys_str_mv AT juliagshaw irondeficiencyanemiafocusoninfectiousdiseasesinlesserdevelopedcountries
AT jenniferffriedman irondeficiencyanemiafocusoninfectiousdiseasesinlesserdevelopedcountries