Focusing on spinal stenosis: emerging discoveries concerning Alendronate-induced risks and genetic drug targets

Focusing on spinal stenosis: emerging discoveries concerning Alendronate-induced risks and genetic drug targets

Abstract Background Spinal stenosis is a common disease in clinical practice, and drug use is one of its potential predisposing factors. Alendronate, a widely used clinical drug for osteoporosis treatment, has the potential to trigger spinal stenosis. Based on the real world, this study aims to deep...

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Bibliographic Details
Main Authors: Nan Yang, Jingkai Di, Xiang Han, Wei Zhang, Xinliang Cui, Haoyu Feng
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Spinal stenosis
Alendronate
Pharmacovigilance analysis
Mendelian randomization
Drug targets
Online Access:https://doi.org/10.1186/s13018-025-05854-5
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