A NMR-Based Metabolomic Approach to Investigate the Antitumor Effects of the Novel [Pt(η1-C2H4OMe)(DMSO)(phen)]+ (phen = 1,10-Phenanthroline) Compound on Neuroblastoma Cancer Cells

A NMR-Based Metabolomic Approach to Investigate the Antitumor Effects of the Novel [Pt(η1-C2H4OMe)(DMSO)(phen)]+ (phen = 1,10-Phenanthroline) Compound on Neuroblastoma Cancer Cells

NMR-based metabolomics is a very effective tool to assess the tumor response to drugs by providing insights for their mode of action. Recently, a novel Pt(II) complex, [Pt(ƞ1-C2H4OMe)(DMSO)(phen)]+ (phen = 1,10-phenanthroline), Pt-EtOMeSOphen, was synthesized and studied for its antitumor activity...

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Bibliographic Details
Main Authors:	Federica De Castro, Erika Stefàno, Erik De Luca, Antonella Muscella, Santo Marsigliante, Michele Benedetti, Francesco Paolo Fanizzi
Format:	Article
Language:	English
Published:	Wiley 2022-01-01
Series:	Bioinorganic Chemistry and Applications
Online Access:	http://dx.doi.org/10.1155/2022/8932137
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