The role of the e3 ligase cbl-B in murine dendritic cells.

The role of the e3 ligase cbl-B in murine dendritic cells.

Dendritic cells (DCs) are potent antigen-presenting cells with a promising potential in cancer immunotherapy. Cbl proteins are E3 ubiquitin ligases and have been implicated in regulating the functional activity of various immune cells. As an example, c-Cbl negatively affects DC activation. We here d...

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Bibliographic Details
Main Authors: Stephanie Wallner, Christina Lutz-Nicoladoni, Christoph H Tripp, Günther Gastl, Gottfried Baier, Josef M Penninger, Patrizia Stoitzner, Dominik Wolf
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0065178&type=printable
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