Associations between environmental exposures and asthma control and exacerbations in young children: a systematic review
Objective To complete a systematic review of the literature describing associations between all environmental exposures and asthma symptoms and exacerbations in children up to mean age of 9 years.Design Systematic review.Setting Reference lists of identified studies and reviews were searched for all...
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2014-02-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/4/2/e003827.full |
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| _version_ | 1832574355995885568 |
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| author | Steve Turner Jon G Ayres Hilary Cowie Smita Dick Emma Doust |
| author_facet | Steve Turner Jon G Ayres Hilary Cowie Smita Dick Emma Doust |
| author_sort | Steve Turner |
| collection | DOAJ |
| description | Objective To complete a systematic review of the literature describing associations between all environmental exposures and asthma symptoms and exacerbations in children up to mean age of 9 years.Design Systematic review.Setting Reference lists of identified studies and reviews were searched for all articles published until November 2013 in electronic databases (MEDLINE, EMBASE, CINAHL, Cochrane Controls Trials Register).Participants Studies were selected which examined a link between exposure to environmental factors and asthma symptoms and exacerbations where the study participants were children with a mean age of ⩽9 years.Primary and secondary outcome measures Indices of asthma symptoms, control and exacerbations.Results A total of 27 studies were identified including eight where inhaled allergens and four where environmental tobacco smoke (ETS) were the exposures of interest. There was evidence that exposure to allergen, ETS, poor air quality and unflued heaters had a modest magnitude of effect (ORs between 2 and 3). There was also evidence of interactions observed between exposures such as allergen and ETS.Conclusions Exposure to inhaled allergens, ETS, unflued heaters and poor air quality has an important effect on exacerbations in young children with asthma and should be minimised or, ideally, avoided. Better understanding of the effect of exposure to damp housing, air conditioning and dietary factors plus interactions between environmental exposures associated with exacerbations is required. |
| format | Article |
| id | doaj-art-208b8c40f0a04f09bea44340ec35a688 |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2014-02-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-208b8c40f0a04f09bea44340ec35a6882025-02-01T17:20:09ZengBMJ Publishing GroupBMJ Open2044-60552014-02-014210.1136/bmjopen-2013-003827Associations between environmental exposures and asthma control and exacerbations in young children: a systematic reviewSteve Turner0Jon G Ayres1Hilary Cowie2Smita Dick3Emma Doust4Women and Children’s Division, NHS Grampian, Aberdeen, UK2 Institute of Occupational and Environmental Medicine, University of Birmingham, Birmingham, West Midlands, UKInstitute of Occupational Medicine, Edinburgh, UK1 Child Health, University of Aberdeen School of Medical Sciences, Aberdeen, UKInstitute of Occupational Medicine, Edinburgh, UKObjective To complete a systematic review of the literature describing associations between all environmental exposures and asthma symptoms and exacerbations in children up to mean age of 9 years.Design Systematic review.Setting Reference lists of identified studies and reviews were searched for all articles published until November 2013 in electronic databases (MEDLINE, EMBASE, CINAHL, Cochrane Controls Trials Register).Participants Studies were selected which examined a link between exposure to environmental factors and asthma symptoms and exacerbations where the study participants were children with a mean age of ⩽9 years.Primary and secondary outcome measures Indices of asthma symptoms, control and exacerbations.Results A total of 27 studies were identified including eight where inhaled allergens and four where environmental tobacco smoke (ETS) were the exposures of interest. There was evidence that exposure to allergen, ETS, poor air quality and unflued heaters had a modest magnitude of effect (ORs between 2 and 3). There was also evidence of interactions observed between exposures such as allergen and ETS.Conclusions Exposure to inhaled allergens, ETS, unflued heaters and poor air quality has an important effect on exacerbations in young children with asthma and should be minimised or, ideally, avoided. Better understanding of the effect of exposure to damp housing, air conditioning and dietary factors plus interactions between environmental exposures associated with exacerbations is required.https://bmjopen.bmj.com/content/4/2/e003827.full |
| spellingShingle | Steve Turner Jon G Ayres Hilary Cowie Smita Dick Emma Doust Associations between environmental exposures and asthma control and exacerbations in young children: a systematic review BMJ Open |
| title | Associations between environmental exposures and asthma control and exacerbations in young children: a systematic review |
| title_full | Associations between environmental exposures and asthma control and exacerbations in young children: a systematic review |
| title_fullStr | Associations between environmental exposures and asthma control and exacerbations in young children: a systematic review |
| title_full_unstemmed | Associations between environmental exposures and asthma control and exacerbations in young children: a systematic review |
| title_short | Associations between environmental exposures and asthma control and exacerbations in young children: a systematic review |
| title_sort | associations between environmental exposures and asthma control and exacerbations in young children a systematic review |
| url | https://bmjopen.bmj.com/content/4/2/e003827.full |
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