PLAC8 attenuates pulmonary fibrosis and inhibits apoptosis of alveolar epithelial cells via facilitating autophagy
Abstract Idiopathic pulmonary fibrosis (IPF) is an irreversible lung condition that progresses over time, which ultimately results in respiratory failure and mortality. In this study, we found that PLAC8 was downregulated in the lungs of IPF patients based on GEO data, in bleomycin (BLM)-induced lun...
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Main Authors: | Wei Sun, Bo Zhao, Zhong He, Lihua Chang, Wei Song, Yingying Chen |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-024-07334-8 |
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