Uncommon Cause of Psychotic Behavior in a 9-Year-Old Girl: A Case Report

Anti-N-methyl-D-aspartate receptors encephalitis (ANMDARE) is a well-defined, life threatening, but treatable disorder that often occurs as a paraneoplastic manifestation of ovarian teratomas in adult women. We report a child with this disorder who displayed a subacute onset of delirium, seizures,...

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Main Authors: Willemina K. Van Putten, Said Hachimi-Idrissi, Anna Jansen, Viola Van Gorp, Luc Huyghens
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2012/358520
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author Willemina K. Van Putten
Said Hachimi-Idrissi
Anna Jansen
Viola Van Gorp
Luc Huyghens
author_facet Willemina K. Van Putten
Said Hachimi-Idrissi
Anna Jansen
Viola Van Gorp
Luc Huyghens
author_sort Willemina K. Van Putten
collection DOAJ
description Anti-N-methyl-D-aspartate receptors encephalitis (ANMDARE) is a well-defined, life threatening, but treatable disorder that often occurs as a paraneoplastic manifestation of ovarian teratomas in adult women. We report a child with this disorder who displayed a subacute onset of delirium, seizures, and autonomic instability. Antibodies against NMDA receptor were detectable in the serum and in the cerebrospinal fluid. No teratoma or other tumour was detected. We speculate that the previous viral/mycoplasma infection may be the trigger of this encephalitis. This patient showed a reversal of the neurological symptoms after intravenous immunoglobulin. Prompt recognition of this disorder followed by immunotherapy results in full neurological recovery.
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issn 1687-9627
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spelling doaj-art-2063a0734fcc4e5e881bb2236d1f381a2025-02-03T00:59:47ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/358520358520Uncommon Cause of Psychotic Behavior in a 9-Year-Old Girl: A Case ReportWillemina K. Van Putten0Said Hachimi-Idrissi1Anna Jansen2Viola Van Gorp3Luc Huyghens4Paediatric Intensive Care Unit, Brussels University Hospital, Laarbeeklaan 101, 1090 Brussels, BelgiumPaediatric Intensive Care Unit, Brussels University Hospital, Laarbeeklaan 101, 1090 Brussels, BelgiumPaediatric Intensive Care Unit, Brussels University Hospital, Laarbeeklaan 101, 1090 Brussels, BelgiumPaediatric Intensive Care Unit, Brussels University Hospital, Laarbeeklaan 101, 1090 Brussels, BelgiumPaediatric Intensive Care Unit, Brussels University Hospital, Laarbeeklaan 101, 1090 Brussels, BelgiumAnti-N-methyl-D-aspartate receptors encephalitis (ANMDARE) is a well-defined, life threatening, but treatable disorder that often occurs as a paraneoplastic manifestation of ovarian teratomas in adult women. We report a child with this disorder who displayed a subacute onset of delirium, seizures, and autonomic instability. Antibodies against NMDA receptor were detectable in the serum and in the cerebrospinal fluid. No teratoma or other tumour was detected. We speculate that the previous viral/mycoplasma infection may be the trigger of this encephalitis. This patient showed a reversal of the neurological symptoms after intravenous immunoglobulin. Prompt recognition of this disorder followed by immunotherapy results in full neurological recovery.http://dx.doi.org/10.1155/2012/358520
spellingShingle Willemina K. Van Putten
Said Hachimi-Idrissi
Anna Jansen
Viola Van Gorp
Luc Huyghens
Uncommon Cause of Psychotic Behavior in a 9-Year-Old Girl: A Case Report
Case Reports in Medicine
title Uncommon Cause of Psychotic Behavior in a 9-Year-Old Girl: A Case Report
title_full Uncommon Cause of Psychotic Behavior in a 9-Year-Old Girl: A Case Report
title_fullStr Uncommon Cause of Psychotic Behavior in a 9-Year-Old Girl: A Case Report
title_full_unstemmed Uncommon Cause of Psychotic Behavior in a 9-Year-Old Girl: A Case Report
title_short Uncommon Cause of Psychotic Behavior in a 9-Year-Old Girl: A Case Report
title_sort uncommon cause of psychotic behavior in a 9 year old girl a case report
url http://dx.doi.org/10.1155/2012/358520
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