Chinese stroke association guidelines on reperfusion therapy for acute ischaemic stroke 2024
Background Stroke remains a major global health challenge, with China experiencing a significant burden due to its high incidence and severe outcomes. Reperfusion therapies, such as intravenous thrombolysis and endovascular thrombectomy, have shown substantial benefits in improving early outcomes fo...
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| Language: | English |
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BMJ Publishing Group
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| Series: | Stroke and Vascular Neurology |
| Online Access: | https://svn.bmj.com/content/early/2025/01/19/svn-2024-003977.full |
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| author | Liping Liu Anding Xu Xin Wang Yongjun Wang Yilong Wang Zhongrong Miao Yuming Xu Benyan Luo Bin Peng Yong Huo Qiang Dong Zixiao Li Xingquan Zhao Caiyun Wang Hongqiu Gu Chunjuan Wang Zhengqi Lu Yunyun Xiong Shuo Wang Lihua Wang Linong Ji Xiaoping Gao Wenzhi Wang Yi Yang Kai Wang Junbo Ge Xunming Ji Jun Pu Tong Zhang Bo Hu Ning Wang Yun Xu Jinsheng Zeng Gang Zhao Zhong Chen Aoming Jin Xiaoyuan Niu Jiong Shi Shuya Li Jianmin Zhang Ling Yin Dou Li Dehong Lu Chao Qin Dapeng Sun Kaifu Ke Yanhui Du Xiaoning Zhang Fudong Shi Jianxin Zhou Lan Chu Li Guo Li He Shengnian Zhou Weixin Cai Xiaomu Wu Zhiyi He |
| author_facet | Liping Liu Anding Xu Xin Wang Yongjun Wang Yilong Wang Zhongrong Miao Yuming Xu Benyan Luo Bin Peng Yong Huo Qiang Dong Zixiao Li Xingquan Zhao Caiyun Wang Hongqiu Gu Chunjuan Wang Zhengqi Lu Yunyun Xiong Shuo Wang Lihua Wang Linong Ji Xiaoping Gao Wenzhi Wang Yi Yang Kai Wang Junbo Ge Xunming Ji Jun Pu Tong Zhang Bo Hu Ning Wang Yun Xu Jinsheng Zeng Gang Zhao Zhong Chen Aoming Jin Xiaoyuan Niu Jiong Shi Shuya Li Jianmin Zhang Ling Yin Dou Li Dehong Lu Chao Qin Dapeng Sun Kaifu Ke Yanhui Du Xiaoning Zhang Fudong Shi Jianxin Zhou Lan Chu Li Guo Li He Shengnian Zhou Weixin Cai Xiaomu Wu Zhiyi He |
| collection | DOAJ |
| description | Background Stroke remains a major global health challenge, with China experiencing a significant burden due to its high incidence and severe outcomes. Reperfusion therapies, such as intravenous thrombolysis and endovascular thrombectomy, have shown substantial benefits in improving early outcomes for ischaemic stroke. Recent clinical trials have validated the safety and efficacy of a broader range of thrombolytic agents and expanded the eligible patient populations for both intravenous thrombolysis and mechanical thrombectomy. This guideline aims to provide the latest evidence-based insights in the field of reperfusion therapy.Methods The Chinese Stroke Association (CSA) established a writing group to develop updated guidelines on reperfusion therapy for acute ischaemic stroke. A comprehensive search of MEDLINE (via PubMed) was conducted up to 30 September 2024. Experts in the field of stroke engaged in extensive discussions, both online and offline, to evaluate the latest evidence. Each recommendation was graded using the CSA’s class of recommendation and level of evidence in the Guideline Development Manual of the CSA.Results This guideline, reviewed and approved by the CSA Guidelines Writing Group, outlines the criteria for patient selection for thrombolysis and thrombectomy and summarises the latest evidence on various thrombolytic drug options to support decision-making in reperfusion therapy. Additionally, the guideline includes green channel flow charts for intravenous thrombolysis and mechanical thrombectomy, designed to assist clinicians in optimising their clinical decisions.Conclusion This guideline updates the latest advancements in the field of reperfusion therapy for acute ischaemic stroke. It is anticipated that future clinical research will further advance areas such as innovative thrombolytic agents, expanded indications for thrombolysis and mechanical thrombectomy. |
| format | Article |
| id | doaj-art-20595fc2566b410ea6a38a7fbc27ce39 |
| institution | Kabale University |
| issn | 2059-8696 |
| language | English |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | Stroke and Vascular Neurology |
| spelling | doaj-art-20595fc2566b410ea6a38a7fbc27ce392025-01-21T11:30:08ZengBMJ Publishing GroupStroke and Vascular Neurology2059-869610.1136/svn-2024-003977Chinese stroke association guidelines on reperfusion therapy for acute ischaemic stroke 2024 Liping Liu0Anding XuXin WangYongjun Wang1Yilong WangZhongrong Miao2Yuming XuBenyan LuoBin PengYong HuoQiang Dong3Zixiao Li4Xingquan ZhaoCaiyun WangHongqiu Gu5Chunjuan Wang6Zhengqi LuYunyun Xiong7Shuo WangLihua WangLinong JiXiaoping GaoWenzhi WangYi YangKai WangJunbo GeXunming JiJun PuTong ZhangBo HuNing WangYun XuJinsheng Zeng8Gang ZhaoZhong ChenAoming Jin9Xiaoyuan NiuJiong ShiShuya Li10Jianmin ZhangLing YinDou LiDehong LuChao QinDapeng Sun11Kaifu KeYanhui DuXiaoning ZhangFudong ShiJianxin ZhouLan ChuLi Guo Li HeShengnian ZhouWeixin CaiXiaomu WuZhiyi HeDepartment of Neurology, Beijing Tiantan Hospital, Beijing, ChinaDepartment of Neurology, Beijing Tiantan Hospital, Beijing, ChinaDepartment of Neurology, Beijing Tiantan Hospital, Beijing, ChinaDepartment of Neurology, Huashan Hospital Fudan University, Shanghai, ChinaChina National Clinical Research Center for Neurological Diseases, Beijing, ChinaChina National Clinical Research Center for Neurological Diseases, Beijing, ChinaDepartment of Neurology, Beijing Tiantan Hospital, Beijing, ChinaDepartment of Neurology, Beijing Tiantan Hospital, Beijing, ChinaNeurology, Sun Yat-sen University First Affiliated Hospital, Guangzhou, Guangdong, ChinaChina National Clinical Research Center for Neurological Diseases, Beijing, ChinaDepartment of Neurology, Beijing Tiantan Hospital, Beijing, ChinaDepartment of Neurology, Beijing Tiantan Hospital, Beijing, ChinaBackground Stroke remains a major global health challenge, with China experiencing a significant burden due to its high incidence and severe outcomes. Reperfusion therapies, such as intravenous thrombolysis and endovascular thrombectomy, have shown substantial benefits in improving early outcomes for ischaemic stroke. Recent clinical trials have validated the safety and efficacy of a broader range of thrombolytic agents and expanded the eligible patient populations for both intravenous thrombolysis and mechanical thrombectomy. This guideline aims to provide the latest evidence-based insights in the field of reperfusion therapy.Methods The Chinese Stroke Association (CSA) established a writing group to develop updated guidelines on reperfusion therapy for acute ischaemic stroke. A comprehensive search of MEDLINE (via PubMed) was conducted up to 30 September 2024. Experts in the field of stroke engaged in extensive discussions, both online and offline, to evaluate the latest evidence. Each recommendation was graded using the CSA’s class of recommendation and level of evidence in the Guideline Development Manual of the CSA.Results This guideline, reviewed and approved by the CSA Guidelines Writing Group, outlines the criteria for patient selection for thrombolysis and thrombectomy and summarises the latest evidence on various thrombolytic drug options to support decision-making in reperfusion therapy. Additionally, the guideline includes green channel flow charts for intravenous thrombolysis and mechanical thrombectomy, designed to assist clinicians in optimising their clinical decisions.Conclusion This guideline updates the latest advancements in the field of reperfusion therapy for acute ischaemic stroke. It is anticipated that future clinical research will further advance areas such as innovative thrombolytic agents, expanded indications for thrombolysis and mechanical thrombectomy.https://svn.bmj.com/content/early/2025/01/19/svn-2024-003977.full |
| spellingShingle | Liping Liu Anding Xu Xin Wang Yongjun Wang Yilong Wang Zhongrong Miao Yuming Xu Benyan Luo Bin Peng Yong Huo Qiang Dong Zixiao Li Xingquan Zhao Caiyun Wang Hongqiu Gu Chunjuan Wang Zhengqi Lu Yunyun Xiong Shuo Wang Lihua Wang Linong Ji Xiaoping Gao Wenzhi Wang Yi Yang Kai Wang Junbo Ge Xunming Ji Jun Pu Tong Zhang Bo Hu Ning Wang Yun Xu Jinsheng Zeng Gang Zhao Zhong Chen Aoming Jin Xiaoyuan Niu Jiong Shi Shuya Li Jianmin Zhang Ling Yin Dou Li Dehong Lu Chao Qin Dapeng Sun Kaifu Ke Yanhui Du Xiaoning Zhang Fudong Shi Jianxin Zhou Lan Chu Li Guo Li He Shengnian Zhou Weixin Cai Xiaomu Wu Zhiyi He Chinese stroke association guidelines on reperfusion therapy for acute ischaemic stroke 2024 Stroke and Vascular Neurology |
| title | Chinese stroke association guidelines on reperfusion therapy for acute ischaemic stroke 2024 |
| title_full | Chinese stroke association guidelines on reperfusion therapy for acute ischaemic stroke 2024 |
| title_fullStr | Chinese stroke association guidelines on reperfusion therapy for acute ischaemic stroke 2024 |
| title_full_unstemmed | Chinese stroke association guidelines on reperfusion therapy for acute ischaemic stroke 2024 |
| title_short | Chinese stroke association guidelines on reperfusion therapy for acute ischaemic stroke 2024 |
| title_sort | chinese stroke association guidelines on reperfusion therapy for acute ischaemic stroke 2024 |
| url | https://svn.bmj.com/content/early/2025/01/19/svn-2024-003977.full |
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