Chemical Space Exploration and Machine Learning-Based Screening of PDE7A Inhibitors
<b>Background/Objectives</b>: Phosphodiesterase 7 (PDE7), a member of the PDE superfamily, selectively catalyzes the hydrolysis of cyclic adenosine 3′,5′-monophosphate (cAMP), thereby regulating the intracellular levels of this second messenger and influencing various physiological funct...
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| Main Authors: | Yuze Li, Zhe Wang, Shengyao Ma, Xiaowen Tang, Hanting Zhang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-03-01
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| Series: | Pharmaceuticals |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1424-8247/18/4/444 |
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