Phospholipase A2 Activity in Gingival Crevicular Fluid from Patients with Periodontal Disease: A possible Marker of Disease Activity
The activity of phospholipase A2 in human gingival crevicular fluid (GCF) associated with periodontal disease was demonstrated. Based upon the presence or absence of bleeding on probing (BOP), which is a marker for the disease activity, there were higher levels of the enzyme activity in BOP positive...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
1994-01-01
|
| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/S0962935194000037 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | The activity of phospholipase A2 in human gingival crevicular fluid
(GCF) associated with periodontal disease was demonstrated. Based
upon the presence or absence of bleeding on probing (BOP), which is
a marker for the disease activity, there were higher levels of the
enzyme activity in BOP positive, than in negative sites. When the
BOP positive sites became negative after periodontal therapy, the
enzyme activity decreased dramatically to almost undetectable
levels. There were no significant differences between the activity
before and after treatment when the BOP positive sites remained
unchanged. These results suggest that the activity in GCF reflects
periodontal disease conditions and that it can be used as a marker
for disease activity. |
|---|---|
| ISSN: | 0962-9351 1466-1861 |