A Straightforward and High-Yielding Synthesis of 1,2,4-Oxadiazoles from Chiral N-Protected α-Amino Acids and Amidoximes in Acetone-Water: An Eco-Friendly Approach
A straightforward and high-yielding methodology for the synthesis of a high structural diversity of 1,2,4-oxadiazoles from different chiral N-protected α-amino acids and amidoximes under microwave (MW) irradiation is described herein. This greener approach gives the desired products using acetone/wa...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2019/8589325 |
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| author | André C. Sauer Lucas Wolf Natália Quoos Mariele B. Rodrigues Antônio L. Braga Oscar E. D. Rodrigues Luciano Dornelles |
| author_facet | André C. Sauer Lucas Wolf Natália Quoos Mariele B. Rodrigues Antônio L. Braga Oscar E. D. Rodrigues Luciano Dornelles |
| author_sort | André C. Sauer |
| collection | DOAJ |
| description | A straightforward and high-yielding methodology for the synthesis of a high structural diversity of 1,2,4-oxadiazoles from different chiral N-protected α-amino acids and amidoximes under microwave (MW) irradiation is described herein. This greener approach gives the desired products using acetone/water as solvent in very short reaction times. |
| format | Article |
| id | doaj-art-20376e453e59437dbf341eaea84b7685 |
| institution | Kabale University |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-20376e453e59437dbf341eaea84b76852025-02-03T01:03:10ZengWileyJournal of Chemistry2090-90632090-90712019-01-01201910.1155/2019/85893258589325A Straightforward and High-Yielding Synthesis of 1,2,4-Oxadiazoles from Chiral N-Protected α-Amino Acids and Amidoximes in Acetone-Water: An Eco-Friendly ApproachAndré C. Sauer0Lucas Wolf1Natália Quoos2Mariele B. Rodrigues3Antônio L. Braga4Oscar E. D. Rodrigues5Luciano Dornelles6Departamento de Química, Universidade Federal de Santa Maria, 97105-900 Santa Maria, RS, BrazilDepartamento de Química, Universidade Federal de Santa Maria, 97105-900 Santa Maria, RS, BrazilDepartamento de Química, Universidade Federal de Santa Maria, 97105-900 Santa Maria, RS, BrazilDepartamento de Química, Universidade Federal de Santa Maria, 97105-900 Santa Maria, RS, BrazilDepartamento de Química, Universidade Federal de Santa Catarina, P.O Box 476, 88040-900 Florianópolis, SC, BrazilDepartamento de Química, Universidade Federal de Santa Maria, 97105-900 Santa Maria, RS, BrazilDepartamento de Química, Universidade Federal de Santa Maria, 97105-900 Santa Maria, RS, BrazilA straightforward and high-yielding methodology for the synthesis of a high structural diversity of 1,2,4-oxadiazoles from different chiral N-protected α-amino acids and amidoximes under microwave (MW) irradiation is described herein. This greener approach gives the desired products using acetone/water as solvent in very short reaction times.http://dx.doi.org/10.1155/2019/8589325 |
| spellingShingle | André C. Sauer Lucas Wolf Natália Quoos Mariele B. Rodrigues Antônio L. Braga Oscar E. D. Rodrigues Luciano Dornelles A Straightforward and High-Yielding Synthesis of 1,2,4-Oxadiazoles from Chiral N-Protected α-Amino Acids and Amidoximes in Acetone-Water: An Eco-Friendly Approach Journal of Chemistry |
| title | A Straightforward and High-Yielding Synthesis of 1,2,4-Oxadiazoles from Chiral N-Protected α-Amino Acids and Amidoximes in Acetone-Water: An Eco-Friendly Approach |
| title_full | A Straightforward and High-Yielding Synthesis of 1,2,4-Oxadiazoles from Chiral N-Protected α-Amino Acids and Amidoximes in Acetone-Water: An Eco-Friendly Approach |
| title_fullStr | A Straightforward and High-Yielding Synthesis of 1,2,4-Oxadiazoles from Chiral N-Protected α-Amino Acids and Amidoximes in Acetone-Water: An Eco-Friendly Approach |
| title_full_unstemmed | A Straightforward and High-Yielding Synthesis of 1,2,4-Oxadiazoles from Chiral N-Protected α-Amino Acids and Amidoximes in Acetone-Water: An Eco-Friendly Approach |
| title_short | A Straightforward and High-Yielding Synthesis of 1,2,4-Oxadiazoles from Chiral N-Protected α-Amino Acids and Amidoximes in Acetone-Water: An Eco-Friendly Approach |
| title_sort | straightforward and high yielding synthesis of 1 2 4 oxadiazoles from chiral n protected α amino acids and amidoximes in acetone water an eco friendly approach |
| url | http://dx.doi.org/10.1155/2019/8589325 |
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