Eosinophilic Gastritis in a Patient Previously Treated with Dupilumab
A 77-year-old Japanese man with bronchial asthma was treated with dupilumab. Dupilumab treatment was discontinued at the patient’s request after two injections separated by a 2-week interval. The blood eosinophil count was elevated, and an esophagogastroduodenoscopy performed 3 months after dupiluma...
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Format: | Article |
Language: | English |
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Wiley
2020-01-01
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Series: | Case Reports in Gastrointestinal Medicine |
Online Access: | http://dx.doi.org/10.1155/2020/6381670 |
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author | Masaya Iwamuro Toshi Murakami Takehiro Tanaka Shohei Oka Seiji Kawano Yoshiro Kawahara Hiroyuki Okada |
author_facet | Masaya Iwamuro Toshi Murakami Takehiro Tanaka Shohei Oka Seiji Kawano Yoshiro Kawahara Hiroyuki Okada |
author_sort | Masaya Iwamuro |
collection | DOAJ |
description | A 77-year-old Japanese man with bronchial asthma was treated with dupilumab. Dupilumab treatment was discontinued at the patient’s request after two injections separated by a 2-week interval. The blood eosinophil count was elevated, and an esophagogastroduodenoscopy performed 3 months after dupilumab treatment revealed gastric ulcers; subsequently, eosinophilic gastritis was diagnosed from biopsy examinations. The gastric lesions were resolved by steroid administration. This case report underscores that eosinophil-associated gastrointestinal diseases should be considered in the differential diagnosis of gastric lesions occurring in patients who were treated with dupilumab. |
format | Article |
id | doaj-art-202eb99e32464e5e9b78aa85c02be8dd |
institution | Kabale University |
issn | 2090-6528 2090-6536 |
language | English |
publishDate | 2020-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Gastrointestinal Medicine |
spelling | doaj-art-202eb99e32464e5e9b78aa85c02be8dd2025-02-03T01:01:27ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362020-01-01202010.1155/2020/63816706381670Eosinophilic Gastritis in a Patient Previously Treated with DupilumabMasaya Iwamuro0Toshi Murakami1Takehiro Tanaka2Shohei Oka3Seiji Kawano4Yoshiro Kawahara5Hiroyuki Okada6Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, JapanSatsuki Naika Clinic, Okayama 703-8258, JapanDepartment of Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, JapanDepartment of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, JapanDepartment of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, JapanDepartment of Practical Gastrointestinal Endoscopy, Okayama University Hospital, Okayama 700-8558, JapanDepartment of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, JapanA 77-year-old Japanese man with bronchial asthma was treated with dupilumab. Dupilumab treatment was discontinued at the patient’s request after two injections separated by a 2-week interval. The blood eosinophil count was elevated, and an esophagogastroduodenoscopy performed 3 months after dupilumab treatment revealed gastric ulcers; subsequently, eosinophilic gastritis was diagnosed from biopsy examinations. The gastric lesions were resolved by steroid administration. This case report underscores that eosinophil-associated gastrointestinal diseases should be considered in the differential diagnosis of gastric lesions occurring in patients who were treated with dupilumab.http://dx.doi.org/10.1155/2020/6381670 |
spellingShingle | Masaya Iwamuro Toshi Murakami Takehiro Tanaka Shohei Oka Seiji Kawano Yoshiro Kawahara Hiroyuki Okada Eosinophilic Gastritis in a Patient Previously Treated with Dupilumab Case Reports in Gastrointestinal Medicine |
title | Eosinophilic Gastritis in a Patient Previously Treated with Dupilumab |
title_full | Eosinophilic Gastritis in a Patient Previously Treated with Dupilumab |
title_fullStr | Eosinophilic Gastritis in a Patient Previously Treated with Dupilumab |
title_full_unstemmed | Eosinophilic Gastritis in a Patient Previously Treated with Dupilumab |
title_short | Eosinophilic Gastritis in a Patient Previously Treated with Dupilumab |
title_sort | eosinophilic gastritis in a patient previously treated with dupilumab |
url | http://dx.doi.org/10.1155/2020/6381670 |
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