Treating common mental disorder including psychotic experiences in the primary care improving access to psychological therapies programme (the TYPPEX study): protocol for a stepped wedge cluster randomised controlled trial with nested economic and process evaluation of a training package for therapists
Introduction At least one in four people treated by the primary care improving access to psychological therapies (IAPT) programme in England experiences distressing psychotic experiences (PE) in addition to common mental disorder (CMD). These individuals are less likely to achieve recovery. IAPT ser...
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BMJ Publishing Group
2022-06-01
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| author | David Fowler Jesus Perez Peter B Jones Debra Russo Clare Knight Mary Dixon-Woods Allan B Clark Margaret Heslin Sarah Byford Paul French Thomas Kabir Jan Stochl Mona Kanaan James Clarke Nick Grey Ann Marie Swart Polly-Anna Ashford Ushma Patel Freya Stuart Hannah Murray J Hodgekins Nesta Reeve Nicola Marshall Michelle Painter Maria Leathersich Martin Pond |
| author_facet | David Fowler Jesus Perez Peter B Jones Debra Russo Clare Knight Mary Dixon-Woods Allan B Clark Margaret Heslin Sarah Byford Paul French Thomas Kabir Jan Stochl Mona Kanaan James Clarke Nick Grey Ann Marie Swart Polly-Anna Ashford Ushma Patel Freya Stuart Hannah Murray J Hodgekins Nesta Reeve Nicola Marshall Michelle Painter Maria Leathersich Martin Pond |
| author_sort | David Fowler |
| collection | DOAJ |
| description | Introduction At least one in four people treated by the primary care improving access to psychological therapies (IAPT) programme in England experiences distressing psychotic experiences (PE) in addition to common mental disorder (CMD). These individuals are less likely to achieve recovery. IAPT services do not routinely screen for nor offer specific treatments for CMD including PE. The Tailoring evidence-based psychological therapY for People with common mental disorder including Psychotic EXperiences study will evaluate the clinical and cost-effectiveness of an enhanced training for cognitive behavioural therapists that aims to address this clinical gap.Methods and analysis This is a multisite, stepped-wedge cluster randomised controlled trial. The setting will be IAPT services within three mental health trusts. The participants will be (1) 56–80 qualified IAPT cognitive behavioural therapists and (2) 600 service users who are triaged as appropriate for cognitive behavioural therapy in an IAPT service and have PE according to the Community Assessment of Psychic Experiences—Positive 15-items Scale. IAPT therapists will be grouped into eight study clusters subsequently randomised to the control-intervention sequence. We will obtain pseudonymous clinical outcome data from IAPT clinical records for eligible service users. We will invite service users to complete health economic measures at baseline, 3, 6, 9 and 12-month follow-up. The primary outcome will be the proportion of patients with common mental disorder psychotic experiences who have recovered by the end of treatment as measured by the official IAPT measure for recovery.Ethics and dissemination The study received the following approvals: South Central—Berkshire Research Ethics Committee on 28 April 2020 (REC reference 20/SC/0135) and Health Research Authority (HRA) on 23 June 2020. An amendment was approved by the Ethics Committee on 01 October 2020 and HRA on 27 October 2020. Results will be made available to patients and the public, the funders, stakeholders in the IAPT services and other researchers.Trial registration number ISRCTN93895792. |
| format | Article |
| id | doaj-art-2006b061447d464d93c9228055b78294 |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | BMJ Publishing Group |
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| series | BMJ Open |
| spelling | doaj-art-2006b061447d464d93c9228055b782942025-01-28T04:10:10ZengBMJ Publishing GroupBMJ Open2044-60552022-06-0112610.1136/bmjopen-2021-056355Treating common mental disorder including psychotic experiences in the primary care improving access to psychological therapies programme (the TYPPEX study): protocol for a stepped wedge cluster randomised controlled trial with nested economic and process evaluation of a training package for therapistsDavid Fowler0Jesus Perez1Peter B Jones2Debra Russo3Clare Knight4Mary Dixon-Woods5Allan B Clark6Margaret Heslin7Sarah Byford8Paul French9Thomas Kabir10Jan Stochl11Mona Kanaan12James Clarke13Nick Grey14Ann Marie Swart15Polly-Anna Ashford16Ushma Patel17Freya Stuart18Hannah Murray19J Hodgekins20Nesta Reeve21Nicola Marshall22Michelle Painter23Maria Leathersich24Martin Pond25Psychology, University of Sussex, Brighton, UKCambridgeshire and Peterborough NHS Foundation Trust, Cambridge, Cambridgeshire, UKNIHR Applied Research Collaboration (ARC) East of England (EoE), Cambridge, UKPsychiatry, University of Cambridge, Cambridge, Cambridgeshire, UKPsychiatry, University of Cambridge, Cambridge, Cambridgeshire, UK1 Department of Public Health and Primary Care, THIS Institute (The Healthcare Improvement Studies Institute), University of Cambridge, Strangeways Research Laboratory, Cambridge, UK1 Norwich Medical School, University of East Anglia, Norwich, UKInstitute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UKKing`s College London, London, UK3 Faculty of Health, Psychology and Social Care, Manchester Metropolitan University, Manchester, UKThe McPin Foundation, London, Greater London, UKDepartment of Psychiatry, University of Cambridge, Cambridge, UKDepartment of Health Sciences, University of York, York, UK2 La Jolla Institute for Immunology, La Jolla, California, USAPsychology, University of Sussex, Brighton, Brighton and Hove, UKNorwich Medical School, University of East Anglia, Norwich, Norfolk, UKNorwich Medical School, University of East Anglia, Norwich, UKCambridgeshire and Peterborough NHS Foundation Trust, Fulbourn, Cambridgeshire, UKPsychiatry, University of Cambridge, Cambridge, Cambridgeshire, UKPsychology, University of Oxford, Oxford, UKNorwich Medical School, University of East Anglia, Norwich, Norfolk, UKNorfolk and Suffolk NHS Foundation Trust, Norwich, Norfolk, UKCambridgeshire and Peterborough NHS Foundation Trust, Fulbourn, Cambridgeshire, UKNorfolk and Suffolk NHS Foundation Trust, Norwich, Norfolk, UKNorwich Medical School, University of East Anglia, Norwich, Norfolk, UKNorwich Medical School, University of East Anglia, Norwich, Norfolk, UKIntroduction At least one in four people treated by the primary care improving access to psychological therapies (IAPT) programme in England experiences distressing psychotic experiences (PE) in addition to common mental disorder (CMD). These individuals are less likely to achieve recovery. IAPT services do not routinely screen for nor offer specific treatments for CMD including PE. The Tailoring evidence-based psychological therapY for People with common mental disorder including Psychotic EXperiences study will evaluate the clinical and cost-effectiveness of an enhanced training for cognitive behavioural therapists that aims to address this clinical gap.Methods and analysis This is a multisite, stepped-wedge cluster randomised controlled trial. The setting will be IAPT services within three mental health trusts. The participants will be (1) 56–80 qualified IAPT cognitive behavioural therapists and (2) 600 service users who are triaged as appropriate for cognitive behavioural therapy in an IAPT service and have PE according to the Community Assessment of Psychic Experiences—Positive 15-items Scale. IAPT therapists will be grouped into eight study clusters subsequently randomised to the control-intervention sequence. We will obtain pseudonymous clinical outcome data from IAPT clinical records for eligible service users. We will invite service users to complete health economic measures at baseline, 3, 6, 9 and 12-month follow-up. The primary outcome will be the proportion of patients with common mental disorder psychotic experiences who have recovered by the end of treatment as measured by the official IAPT measure for recovery.Ethics and dissemination The study received the following approvals: South Central—Berkshire Research Ethics Committee on 28 April 2020 (REC reference 20/SC/0135) and Health Research Authority (HRA) on 23 June 2020. An amendment was approved by the Ethics Committee on 01 October 2020 and HRA on 27 October 2020. Results will be made available to patients and the public, the funders, stakeholders in the IAPT services and other researchers.Trial registration number ISRCTN93895792.https://bmjopen.bmj.com/content/12/6/e056355.full |
| spellingShingle | David Fowler Jesus Perez Peter B Jones Debra Russo Clare Knight Mary Dixon-Woods Allan B Clark Margaret Heslin Sarah Byford Paul French Thomas Kabir Jan Stochl Mona Kanaan James Clarke Nick Grey Ann Marie Swart Polly-Anna Ashford Ushma Patel Freya Stuart Hannah Murray J Hodgekins Nesta Reeve Nicola Marshall Michelle Painter Maria Leathersich Martin Pond Treating common mental disorder including psychotic experiences in the primary care improving access to psychological therapies programme (the TYPPEX study): protocol for a stepped wedge cluster randomised controlled trial with nested economic and process evaluation of a training package for therapists BMJ Open |
| title | Treating common mental disorder including psychotic experiences in the primary care improving access to psychological therapies programme (the TYPPEX study): protocol for a stepped wedge cluster randomised controlled trial with nested economic and process evaluation of a training package for therapists |
| title_full | Treating common mental disorder including psychotic experiences in the primary care improving access to psychological therapies programme (the TYPPEX study): protocol for a stepped wedge cluster randomised controlled trial with nested economic and process evaluation of a training package for therapists |
| title_fullStr | Treating common mental disorder including psychotic experiences in the primary care improving access to psychological therapies programme (the TYPPEX study): protocol for a stepped wedge cluster randomised controlled trial with nested economic and process evaluation of a training package for therapists |
| title_full_unstemmed | Treating common mental disorder including psychotic experiences in the primary care improving access to psychological therapies programme (the TYPPEX study): protocol for a stepped wedge cluster randomised controlled trial with nested economic and process evaluation of a training package for therapists |
| title_short | Treating common mental disorder including psychotic experiences in the primary care improving access to psychological therapies programme (the TYPPEX study): protocol for a stepped wedge cluster randomised controlled trial with nested economic and process evaluation of a training package for therapists |
| title_sort | treating common mental disorder including psychotic experiences in the primary care improving access to psychological therapies programme the typpex study protocol for a stepped wedge cluster randomised controlled trial with nested economic and process evaluation of a training package for therapists |
| url | https://bmjopen.bmj.com/content/12/6/e056355.full |
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