Novel loci for triglyceride/HDL-C ratio longitudinal change among subjects without T2D

Novel loci for triglyceride/HDL-C ratio longitudinal change among subjects without T2D

Triglyceride (TG)/HDL-C ratio (THR) is a surrogate predictor of hyperinsulinemia. To identify novel genetic loci for THR change over time (ΔTHR), we conducted genome-wide association study (GWAS) and genome-wide linkage scan (GWLS) among nondiabetic Europeans from the Long Life Family Study (n = 1,3...

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Bibliographic Details
Main Authors: Lihua Wang, Siyu Wang, Jason A. Anema, Vaha A. Moghaddam, Yanli Lu, Shiow Lin, E. Warwick Daw, Allison L. Kuipers, Iva Miljkovic, Michael Brent, Gary J. Patti, Bharat Thygarajan, Joseph M. Zmuda, Michael A. Province, Ping An
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Journal of Lipid Research
Subjects:
insulin resistance
aging
genome-wide linkage scan
GWAS
multiomics analyses
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227524002074
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