Botulinum Neurotoxin Application to the Severed Femoral Nerve Modulates Spinal Synaptic Responses to Axotomy and Enhances Motor Recovery in Rats
Botulinum neurotoxin A (BoNT) and brain-derived neurotrophic factor (BDNF) are known for their ability to influence synaptic inputs to neurons. Here, we tested if these drugs can modulate the deafferentation of motoneurons following nerve section/suture and, as a consequence, modify the outcome of p...
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Main Authors: | Marcel Irintchev, Orlando Guntinas-Lichius, Andrey Irintchev |
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Format: | Article |
Language: | English |
Published: |
Wiley
2018-01-01
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Series: | Neural Plasticity |
Online Access: | http://dx.doi.org/10.1155/2018/7975013 |
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