Fibroblast Activation Protein Acts as a Biomarker for Monitoring ECM Remodeling During Aortic Aneurysm via 68Ga‐FAPI‐04 PET Imaging

Fibroblast Activation Protein Acts as a Biomarker for Monitoring ECM Remodeling During Aortic Aneurysm via 68Ga‐FAPI‐04 PET Imaging

Abstract Traditional imaging modalities used to monitor the diameter of aortic aneurysms (AAs) often fail to follow pathological progression. Fibroblast activation protein (FAP), a key regulator of extracellular matrix (ECM) remodeling, plays a pivotal role in aortic disease. However, its expression...

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Main Authors: Chengkai Hu, Hui Tan, Yuchong Zhang, Genmao Cao, Chenye Wu, Peng Lin, Shouji Qiu, Fandi Mo, Enci Wang, Shiyi Li, Tong Yuan, Zheyun Li, Weiguo Fu, Dengfeng Cheng, Hao Lai, Xiaoyuan Chen, Lixin Wang
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Advanced Science
Subjects:
aortic aneurysm
extracellular matrix
fibroblast activation protein
positron emission tomography imaging
Online Access:https://doi.org/10.1002/advs.202411152
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