The transcription factor IID subunit Taf13 is dispensable for TATA binding protein promoter recruitment and RNA polymerase II transcription

The transcription factor IID subunit Taf13 is dispensable for TATA binding protein promoter recruitment and RNA polymerase II transcription

Summary: The multiprotein complex TFIID, comprising the TATA binding protein (TBP) and 13 TBP-associated factors (TAFs), is an essential component of the RNA polymerase II (Pol II) preinitiation complex (PIC). Cryo-electron microscopy studies suggested a critical role of the TAF11-TAF13 heterodimer...

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Bibliographic Details
Main Authors: Igor Martianov, Stephanie Le Gras, Guillaume Davidson, Irwin Davidson
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:iScience
Subjects:
Biochemistry
Molecular biology
Developmental biology
Embryology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225005474
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