Seizure and Hepatosplenomegaly—Rare Manifestation of Parvovirus B-19: A Case Report and Review of the Literature
Parvovirus B19 is the etiologic agent of erythema infectiosum (fifth disease), a fever-rash illness occurring in childhood. We present a 10 month old child with high grade fever for 10 days, generalized tonic-clonic seizure, bilateral cervical lymphadenopathy, generalized maculopapular rash, hematem...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Journal of Tropical Medicine |
| Online Access: | http://dx.doi.org/10.1155/2011/287914 |
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| author | Yadav Kamlesh Gupta Pallav Murari Manjula Malik Rohan |
| author_facet | Yadav Kamlesh Gupta Pallav Murari Manjula Malik Rohan |
| author_sort | Yadav Kamlesh |
| collection | DOAJ |
| description | Parvovirus B19 is the etiologic agent of erythema infectiosum (fifth disease), a fever-rash illness
occurring in childhood. We present a 10 month old child with high grade fever for 10 days,
generalized tonic-clonic seizure, bilateral cervical lymphadenopathy, generalized maculopapular
rash, hematemesis and malena. Bone marrow aspiration and liver biopsy were done. EBV
serology and parvovirus PCR were also performed. Bone marrow aspiration and biopsy showed
giant pro-erythroblast consistent with parvovirus infection. PCR showed amplification of
parvovirus genomic sequences. Present case highlights an atypical presentation of Parvovirus
B19 infection as fever, rash and hepatosplenomegaly. |
| format | Article |
| id | doaj-art-1fc4e07e46d84159a7b04de4ccada2fb |
| institution | Kabale University |
| issn | 1687-9686 1687-9694 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Tropical Medicine |
| spelling | doaj-art-1fc4e07e46d84159a7b04de4ccada2fb2025-02-03T01:11:02ZengWileyJournal of Tropical Medicine1687-96861687-96942011-01-01201110.1155/2011/287914287914Seizure and Hepatosplenomegaly—Rare Manifestation of Parvovirus B-19: A Case Report and Review of the LiteratureYadav Kamlesh0Gupta Pallav1Murari Manjula2Malik Rohan3Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, IndiaDepartment of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, IndiaDepartment of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, IndiaDepartment of Pediatric Gastroentology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, IndiaParvovirus B19 is the etiologic agent of erythema infectiosum (fifth disease), a fever-rash illness occurring in childhood. We present a 10 month old child with high grade fever for 10 days, generalized tonic-clonic seizure, bilateral cervical lymphadenopathy, generalized maculopapular rash, hematemesis and malena. Bone marrow aspiration and liver biopsy were done. EBV serology and parvovirus PCR were also performed. Bone marrow aspiration and biopsy showed giant pro-erythroblast consistent with parvovirus infection. PCR showed amplification of parvovirus genomic sequences. Present case highlights an atypical presentation of Parvovirus B19 infection as fever, rash and hepatosplenomegaly.http://dx.doi.org/10.1155/2011/287914 |
| spellingShingle | Yadav Kamlesh Gupta Pallav Murari Manjula Malik Rohan Seizure and Hepatosplenomegaly—Rare Manifestation of Parvovirus B-19: A Case Report and Review of the Literature Journal of Tropical Medicine |
| title | Seizure and Hepatosplenomegaly—Rare Manifestation of Parvovirus B-19: A Case Report and Review of the Literature |
| title_full | Seizure and Hepatosplenomegaly—Rare Manifestation of Parvovirus B-19: A Case Report and Review of the Literature |
| title_fullStr | Seizure and Hepatosplenomegaly—Rare Manifestation of Parvovirus B-19: A Case Report and Review of the Literature |
| title_full_unstemmed | Seizure and Hepatosplenomegaly—Rare Manifestation of Parvovirus B-19: A Case Report and Review of the Literature |
| title_short | Seizure and Hepatosplenomegaly—Rare Manifestation of Parvovirus B-19: A Case Report and Review of the Literature |
| title_sort | seizure and hepatosplenomegaly rare manifestation of parvovirus b 19 a case report and review of the literature |
| url | http://dx.doi.org/10.1155/2011/287914 |
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