Seizure and Hepatosplenomegaly—Rare Manifestation of Parvovirus B-19: A Case Report and Review of the Literature
Parvovirus B19 is the etiologic agent of erythema infectiosum (fifth disease), a fever-rash illness occurring in childhood. We present a 10 month old child with high grade fever for 10 days, generalized tonic-clonic seizure, bilateral cervical lymphadenopathy, generalized maculopapular rash, hematem...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
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| Series: | Journal of Tropical Medicine |
| Online Access: | http://dx.doi.org/10.1155/2011/287914 |
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| Summary: | Parvovirus B19 is the etiologic agent of erythema infectiosum (fifth disease), a fever-rash illness
occurring in childhood. We present a 10 month old child with high grade fever for 10 days,
generalized tonic-clonic seizure, bilateral cervical lymphadenopathy, generalized maculopapular
rash, hematemesis and malena. Bone marrow aspiration and liver biopsy were done. EBV
serology and parvovirus PCR were also performed. Bone marrow aspiration and biopsy showed
giant pro-erythroblast consistent with parvovirus infection. PCR showed amplification of
parvovirus genomic sequences. Present case highlights an atypical presentation of Parvovirus
B19 infection as fever, rash and hepatosplenomegaly. |
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| ISSN: | 1687-9686 1687-9694 |