Effects of Repetitive Hyperbaric Oxygen Treatment in Patients with Acute Cerebral Infarction: A Pilot Study
The role of hyperbaric oxygen therapy (HBOT) in the treatment of acute ischemic stroke is controversial. This prospective study assessed the efficacy and safety of HBOT as adjuvant treatment on 46 acute ischemic stroke in patients who did not receive thrombolytic therapy. The HBOT group (n=16) recei...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/2012/694703 |
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| author | Cheng-Hsin Chen Shao-Yuan Chen Vinchi Wang Chao-Ching Chen Kaw-Chen Wang Chih-Hao Chen Yi-Chien Liu Kuo-Cheng Lu Ping-Keung Yip Wen-Ya Ma Chuan-Chieh Liu |
| author_facet | Cheng-Hsin Chen Shao-Yuan Chen Vinchi Wang Chao-Ching Chen Kaw-Chen Wang Chih-Hao Chen Yi-Chien Liu Kuo-Cheng Lu Ping-Keung Yip Wen-Ya Ma Chuan-Chieh Liu |
| author_sort | Cheng-Hsin Chen |
| collection | DOAJ |
| description | The role of hyperbaric oxygen therapy (HBOT) in the treatment of acute ischemic stroke is controversial. This prospective study assessed the efficacy and safety of HBOT as adjuvant treatment on 46 acute ischemic stroke in patients who did not receive thrombolytic therapy. The HBOT group (n=16) received conventional medical treatment with 10 sessions of adjunctive HBOT within 3–5 days after stroke onset, while the control group (n=30) received the same treatment but without HBOT. Early (around two weeks after onset) and late (one month after onset) outcomes (National Institutes of Health Stroke Scale, NIHSS scores) and efficacy (changes of NIHSS scores) of HBOT were evaluated. The baseline clinical characteristics were similar in both groups. Both early and late outcomes of the HBOT group showed significant difference (P≤0.001). In the control group, there was only significant difference in early outcome (P=0.004). For early efficacy, there was no difference when comparing changes of NIHSS scores between the two groups (P=0.140) but there was statistically significant difference when comparing changes of NIHSS scores at one month (P≤0.001). The HBOT used in this study may be effective for patients with acute ischemic stroke and is a safe and harmless adjunctive treatment. |
| format | Article |
| id | doaj-art-1fad7b363c9847fdb81186285948082a |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-1fad7b363c9847fdb81186285948082a2025-02-03T01:10:35ZengWileyThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/694703694703Effects of Repetitive Hyperbaric Oxygen Treatment in Patients with Acute Cerebral Infarction: A Pilot StudyCheng-Hsin Chen0Shao-Yuan Chen1Vinchi Wang2Chao-Ching Chen3Kaw-Chen Wang4Chih-Hao Chen5Yi-Chien Liu6Kuo-Cheng Lu7Ping-Keung Yip8Wen-Ya Ma9Chuan-Chieh Liu10Department of Internal Medicine, Cardinal Tien Hospital, New Taipei City, TaiwanDepartment of Neurology, Cardinal Tein Hospital, New Taipei City, TaiwanDepartment of Neurology, Cardinal Tein Hospital, New Taipei City, TaiwanDepartment of Neurology, Cardinal Tein Hospital, New Taipei City, TaiwanDepartment of Neurology, Cardinal Tein Hospital, New Taipei City, TaiwanDepartment of Neurology, Cardinal Tein Hospital, New Taipei City, TaiwanDepartment of Neurology, Cardinal Tein Hospital, New Taipei City, TaiwanDepartment of Internal Medicine, Cardinal Tien Hospital, New Taipei City, TaiwanDepartment of Neurology, Cardinal Tein Hospital, New Taipei City, TaiwanDepartment of Internal Medicine, Cardinal Tien Hospital, New Taipei City, TaiwanDepartment of Internal Medicine, Cardinal Tien Hospital, New Taipei City, TaiwanThe role of hyperbaric oxygen therapy (HBOT) in the treatment of acute ischemic stroke is controversial. This prospective study assessed the efficacy and safety of HBOT as adjuvant treatment on 46 acute ischemic stroke in patients who did not receive thrombolytic therapy. The HBOT group (n=16) received conventional medical treatment with 10 sessions of adjunctive HBOT within 3–5 days after stroke onset, while the control group (n=30) received the same treatment but without HBOT. Early (around two weeks after onset) and late (one month after onset) outcomes (National Institutes of Health Stroke Scale, NIHSS scores) and efficacy (changes of NIHSS scores) of HBOT were evaluated. The baseline clinical characteristics were similar in both groups. Both early and late outcomes of the HBOT group showed significant difference (P≤0.001). In the control group, there was only significant difference in early outcome (P=0.004). For early efficacy, there was no difference when comparing changes of NIHSS scores between the two groups (P=0.140) but there was statistically significant difference when comparing changes of NIHSS scores at one month (P≤0.001). The HBOT used in this study may be effective for patients with acute ischemic stroke and is a safe and harmless adjunctive treatment.http://dx.doi.org/10.1100/2012/694703 |
| spellingShingle | Cheng-Hsin Chen Shao-Yuan Chen Vinchi Wang Chao-Ching Chen Kaw-Chen Wang Chih-Hao Chen Yi-Chien Liu Kuo-Cheng Lu Ping-Keung Yip Wen-Ya Ma Chuan-Chieh Liu Effects of Repetitive Hyperbaric Oxygen Treatment in Patients with Acute Cerebral Infarction: A Pilot Study The Scientific World Journal |
| title | Effects of Repetitive Hyperbaric Oxygen Treatment in Patients with Acute Cerebral Infarction: A Pilot Study |
| title_full | Effects of Repetitive Hyperbaric Oxygen Treatment in Patients with Acute Cerebral Infarction: A Pilot Study |
| title_fullStr | Effects of Repetitive Hyperbaric Oxygen Treatment in Patients with Acute Cerebral Infarction: A Pilot Study |
| title_full_unstemmed | Effects of Repetitive Hyperbaric Oxygen Treatment in Patients with Acute Cerebral Infarction: A Pilot Study |
| title_short | Effects of Repetitive Hyperbaric Oxygen Treatment in Patients with Acute Cerebral Infarction: A Pilot Study |
| title_sort | effects of repetitive hyperbaric oxygen treatment in patients with acute cerebral infarction a pilot study |
| url | http://dx.doi.org/10.1100/2012/694703 |
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