Oncogenic Brain Metazoan Parasite Infection
Multiple observations suggest that certain parasitic infections can be oncogenic. Among these, neurocysticercosis is associated with increased risk for gliomas and hematologic malignancies. We report the case of a 71-year-old woman with colocalization of a metazoan parasite, possibly cysticercosis,...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2013/263718 |
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| _version_ | 1849307990304227328 |
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| author | Angela N. Spurgeon Marshall C. Cress Oroszi Gabor Qing-Qing Ding Tomoko Tanaka Douglas C. Miller |
| author_facet | Angela N. Spurgeon Marshall C. Cress Oroszi Gabor Qing-Qing Ding Tomoko Tanaka Douglas C. Miller |
| author_sort | Angela N. Spurgeon |
| collection | DOAJ |
| description | Multiple observations suggest that certain parasitic infections can be oncogenic. Among these, neurocysticercosis is associated with increased risk for gliomas and hematologic malignancies. We report the case of a 71-year-old woman with colocalization of a metazoan parasite, possibly cysticercosis, and a WHO grade IV neuroepithelial tumor with exclusively neuronal differentiation by immunohistochemical stains (immunopositive for synaptophysin, neurofilament protein, and Neu-N and not for GFAP, vimentin, or S100). The colocalization and temporal relationship of these two entities suggest a causal relationship. |
| format | Article |
| id | doaj-art-1faa3440a87f4889b2041df0434a7f51 |
| institution | Kabale University |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-1faa3440a87f4889b2041df0434a7f512025-08-20T03:54:34ZengWileyCase Reports in Neurological Medicine2090-66682090-66762013-01-01201310.1155/2013/263718263718Oncogenic Brain Metazoan Parasite InfectionAngela N. Spurgeon0Marshall C. Cress1Oroszi Gabor2Qing-Qing Ding3Tomoko Tanaka4Douglas C. Miller5Department of Surgery, Division of Neurological Surgery, School of Medicine, University of Missouri, Columbia, MO, USADepartment of Surgery, Division of Neurological Surgery, School of Medicine, University of Missouri, Columbia, MO, USADepartment of Pathology, School of Medicine, University of Missouri, Columbia, MO, USADepartment of Pathology, School of Medicine, University of Missouri, Columbia, MO, USADepartment of Surgery, Division of Neurological Surgery, School of Medicine, University of Missouri, Columbia, MO, USADepartment of Pathology, School of Medicine, University of Missouri, Columbia, MO, USAMultiple observations suggest that certain parasitic infections can be oncogenic. Among these, neurocysticercosis is associated with increased risk for gliomas and hematologic malignancies. We report the case of a 71-year-old woman with colocalization of a metazoan parasite, possibly cysticercosis, and a WHO grade IV neuroepithelial tumor with exclusively neuronal differentiation by immunohistochemical stains (immunopositive for synaptophysin, neurofilament protein, and Neu-N and not for GFAP, vimentin, or S100). The colocalization and temporal relationship of these two entities suggest a causal relationship.http://dx.doi.org/10.1155/2013/263718 |
| spellingShingle | Angela N. Spurgeon Marshall C. Cress Oroszi Gabor Qing-Qing Ding Tomoko Tanaka Douglas C. Miller Oncogenic Brain Metazoan Parasite Infection Case Reports in Neurological Medicine |
| title | Oncogenic Brain Metazoan Parasite Infection |
| title_full | Oncogenic Brain Metazoan Parasite Infection |
| title_fullStr | Oncogenic Brain Metazoan Parasite Infection |
| title_full_unstemmed | Oncogenic Brain Metazoan Parasite Infection |
| title_short | Oncogenic Brain Metazoan Parasite Infection |
| title_sort | oncogenic brain metazoan parasite infection |
| url | http://dx.doi.org/10.1155/2013/263718 |
| work_keys_str_mv | AT angelanspurgeon oncogenicbrainmetazoanparasiteinfection AT marshallccress oncogenicbrainmetazoanparasiteinfection AT oroszigabor oncogenicbrainmetazoanparasiteinfection AT qingqingding oncogenicbrainmetazoanparasiteinfection AT tomokotanaka oncogenicbrainmetazoanparasiteinfection AT douglascmiller oncogenicbrainmetazoanparasiteinfection |