Evaluation of the Safety and Effectiveness of Intense Pulsed Light in the Treatment of Meibomian Gland Dysfunction

Purpose. This study aims to explore the safety and efficacy of a novel treatment-intense pulsed light (IPL) in MGD eyes. Methods. This study is a prospective and open label study. Forty eyes of 40 MGD patients were recruited in the study and received 4 consecutive IPL treatments on day 1, day 15, da...

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Main Authors: Xiaodan Jiang, Huibin Lv, Hang Song, Mingzhou Zhang, Yan Liu, Xiaodan Hu, Xuemin Li, Wei Wang
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2016/1910694
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author Xiaodan Jiang
Huibin Lv
Hang Song
Mingzhou Zhang
Yan Liu
Xiaodan Hu
Xuemin Li
Wei Wang
author_facet Xiaodan Jiang
Huibin Lv
Hang Song
Mingzhou Zhang
Yan Liu
Xiaodan Hu
Xuemin Li
Wei Wang
author_sort Xiaodan Jiang
collection DOAJ
description Purpose. This study aims to explore the safety and efficacy of a novel treatment-intense pulsed light (IPL) in MGD eyes. Methods. This study is a prospective and open label study. Forty eyes of 40 MGD patients were recruited in the study and received 4 consecutive IPL treatments on day 1, day 15, day 45, and day 75. Ten ocular surface symptoms were evaluated with a subjective face score at every visit. Best spectacle corrected visual acuity, intraocular pressure (IOP), conjunctival injection, upper and lower tear meniscus height (TMH), tear break-up time (TBUT), corneal staining, lid margin and meibomian gland assessments, and meibography were also recorded at every visit, as well as the adverse effects on the eye and ocular surface. Results. Significant improvements were observed in single and total ocular surface symptom scores, TBUT, and conjunctival injection at all the visits after the initial IPL treatment (P<0.05). Compared to baseline, the signs of eyelid margin, meibomian gland secretion quality, and expressibility were significantly improved at every visit after treatments. There was no regional and systemic threat observed in any patient. Conclusion. Intense pulsed light (IPL) therapy is a safe and efficient treatment in relieving symptoms and signs of MGD eyes.
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institution Kabale University
issn 2090-004X
2090-0058
language English
publishDate 2016-01-01
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series Journal of Ophthalmology
spelling doaj-art-1fa2c3a2576f48bc9d140a07238ff4b42025-02-03T06:00:34ZengWileyJournal of Ophthalmology2090-004X2090-00582016-01-01201610.1155/2016/19106941910694Evaluation of the Safety and Effectiveness of Intense Pulsed Light in the Treatment of Meibomian Gland DysfunctionXiaodan Jiang0Huibin Lv1Hang Song2Mingzhou Zhang3Yan Liu4Xiaodan Hu5Xuemin Li6Wei Wang7Ophthalmology Department, Peking University Third Hospital, Beijing 100191, ChinaOphthalmology Department, Peking University Third Hospital, Beijing 100191, ChinaOphthalmology Department, Peking University Third Hospital, Beijing 100191, ChinaOphthalmology Department, Peking University Third Hospital, Beijing 100191, ChinaOphthalmology Department, Peking University Third Hospital, Beijing 100191, ChinaOphthalmology Department, Peking University Third Hospital, Beijing 100191, ChinaOphthalmology Department, Peking University Third Hospital, Beijing 100191, ChinaOphthalmology Department, Peking University Third Hospital, Beijing 100191, ChinaPurpose. This study aims to explore the safety and efficacy of a novel treatment-intense pulsed light (IPL) in MGD eyes. Methods. This study is a prospective and open label study. Forty eyes of 40 MGD patients were recruited in the study and received 4 consecutive IPL treatments on day 1, day 15, day 45, and day 75. Ten ocular surface symptoms were evaluated with a subjective face score at every visit. Best spectacle corrected visual acuity, intraocular pressure (IOP), conjunctival injection, upper and lower tear meniscus height (TMH), tear break-up time (TBUT), corneal staining, lid margin and meibomian gland assessments, and meibography were also recorded at every visit, as well as the adverse effects on the eye and ocular surface. Results. Significant improvements were observed in single and total ocular surface symptom scores, TBUT, and conjunctival injection at all the visits after the initial IPL treatment (P<0.05). Compared to baseline, the signs of eyelid margin, meibomian gland secretion quality, and expressibility were significantly improved at every visit after treatments. There was no regional and systemic threat observed in any patient. Conclusion. Intense pulsed light (IPL) therapy is a safe and efficient treatment in relieving symptoms and signs of MGD eyes.http://dx.doi.org/10.1155/2016/1910694
spellingShingle Xiaodan Jiang
Huibin Lv
Hang Song
Mingzhou Zhang
Yan Liu
Xiaodan Hu
Xuemin Li
Wei Wang
Evaluation of the Safety and Effectiveness of Intense Pulsed Light in the Treatment of Meibomian Gland Dysfunction
Journal of Ophthalmology
title Evaluation of the Safety and Effectiveness of Intense Pulsed Light in the Treatment of Meibomian Gland Dysfunction
title_full Evaluation of the Safety and Effectiveness of Intense Pulsed Light in the Treatment of Meibomian Gland Dysfunction
title_fullStr Evaluation of the Safety and Effectiveness of Intense Pulsed Light in the Treatment of Meibomian Gland Dysfunction
title_full_unstemmed Evaluation of the Safety and Effectiveness of Intense Pulsed Light in the Treatment of Meibomian Gland Dysfunction
title_short Evaluation of the Safety and Effectiveness of Intense Pulsed Light in the Treatment of Meibomian Gland Dysfunction
title_sort evaluation of the safety and effectiveness of intense pulsed light in the treatment of meibomian gland dysfunction
url http://dx.doi.org/10.1155/2016/1910694
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