Metformin blocks BIK1-mediated CPK28 phosphorylation and enhances plant immunity

Metformin blocks BIK1-mediated CPK28 phosphorylation and enhances plant immunity

Introduction: Metformin (MET), derived from Galega officinalis, stands as the primary first-line medication for the treatment of type 2 diabetes (T2D). Despite its well-documented benefits in mammalian cellular processes, its functions and underlying mechanisms in plants remain unclear. Objectives:...

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Main Authors: Yazhou Bao, Qian Zhang, Hai Zhu, Yong Pei, Yaning Zhao, Yixin Li, Peiyun Ji, Dandan Du, Hao Peng, Guangyuan Xu, Xiaodan Wang, Zhiyuan Yin, Gan Ai, Xiangxiu Liang, Daolong Dou
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Journal of Advanced Research
Subjects:
Metformin
Plant immunity
CPK28
Phosphorylation
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123224000870
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