Analgesic effect of Dahuang Fuzi Decoction in neuropathic pain through inhibiting TNF-α and PI3K-AKT signaling

Analgesic effect of Dahuang Fuzi Decoction in neuropathic pain through inhibiting TNF-α and PI3K-AKT signaling

BackgroundNeuropathic pain (NeP) presents considerable challenges in terms of effective management and significantly impacts the quality of life for affected patients. The current treatment options for NeP are limited, highlighting the need for alternative therapeutic approaches. Dahuang Fuzi Decoct...

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Bibliographic Details
Main Authors: Jinglian Qu, Qian Gong, Siyu He, Jiuyan Peng, Lingyan Chen, Long Wang, Peng Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Neuroscience
Subjects:
Dahuang Fuzi Decoction
neuropathic pain
TNF signaling pathway
network pharmacology
PI3K-AKT signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2024.1464477/full
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