Late-Onset Neutropenia after Rituximab Treatment for Adult-Onset Nephrotic Syndrome
A 41-year-old woman developed nephrotic syndrome at the age of 32 and was diagnosed with minimal change nephrotic syndrome based on a renal biopsy. Although remission was achieved with administration of prednisolone (PSL) and cyclosporine, the nephrotic syndrome recurred. She was also started on rit...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2019-01-01
|
| Series: | Case Reports in Nephrology |
| Online Access: | http://dx.doi.org/10.1155/2019/3580941 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832554690111340544 |
|---|---|
| author | Mayuko Yamazaki Hidekazu Sugiura Yosuke Iwatani Mizuki Kyoda Hirohiko Nokiba Nobuyuki Amemiya Kosaku Nitta Ken Tsuchiya |
| author_facet | Mayuko Yamazaki Hidekazu Sugiura Yosuke Iwatani Mizuki Kyoda Hirohiko Nokiba Nobuyuki Amemiya Kosaku Nitta Ken Tsuchiya |
| author_sort | Mayuko Yamazaki |
| collection | DOAJ |
| description | A 41-year-old woman developed nephrotic syndrome at the age of 32 and was diagnosed with minimal change nephrotic syndrome based on a renal biopsy. Although remission was achieved with administration of prednisolone (PSL) and cyclosporine, the nephrotic syndrome recurred. She was also started on rituximab (RTX). She developed late-onset neutropenia after RTX treatment (R-LON) and improved 17 days later. Although the majority of R-LON cases undergo spontaneous remission, cases of death have been reported. This report is intended to warn about R-LON, since the use of RTX for adult-onset nephrotic syndrome is expected to increase in the future. |
| format | Article |
| id | doaj-art-1f68a72095f34a97aa11951ea8f35458 |
| institution | Kabale University |
| issn | 2090-6641 2090-665X |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Nephrology |
| spelling | doaj-art-1f68a72095f34a97aa11951ea8f354582025-02-03T05:50:51ZengWileyCase Reports in Nephrology2090-66412090-665X2019-01-01201910.1155/2019/35809413580941Late-Onset Neutropenia after Rituximab Treatment for Adult-Onset Nephrotic SyndromeMayuko Yamazaki0Hidekazu Sugiura1Yosuke Iwatani2Mizuki Kyoda3Hirohiko Nokiba4Nobuyuki Amemiya5Kosaku Nitta6Ken Tsuchiya7Department of Nephrology, Division of Medicine, Saiseikai Kurihashi Hospital, Saitama, JapanDepartment of Nephrology, Division of Medicine, Saiseikai Kurihashi Hospital, Saitama, JapanDepartment of Nephrology, Division of Medicine, Saiseikai Kurihashi Hospital, Saitama, JapanDepartment of Nephrology, Division of Medicine, Saiseikai Kurihashi Hospital, Saitama, JapanDepartment of Nephrology, Division of Medicine, Saiseikai Kurihashi Hospital, Saitama, JapanDepartment of Nephrology, Division of Medicine, Saiseikai Kurihashi Hospital, Saitama, JapanDepartment of Nephrology, Tokyo Women’s Medical University, Tokyo, JapanDepartment of Nephrology, Tokyo Women’s Medical University, Tokyo, JapanA 41-year-old woman developed nephrotic syndrome at the age of 32 and was diagnosed with minimal change nephrotic syndrome based on a renal biopsy. Although remission was achieved with administration of prednisolone (PSL) and cyclosporine, the nephrotic syndrome recurred. She was also started on rituximab (RTX). She developed late-onset neutropenia after RTX treatment (R-LON) and improved 17 days later. Although the majority of R-LON cases undergo spontaneous remission, cases of death have been reported. This report is intended to warn about R-LON, since the use of RTX for adult-onset nephrotic syndrome is expected to increase in the future.http://dx.doi.org/10.1155/2019/3580941 |
| spellingShingle | Mayuko Yamazaki Hidekazu Sugiura Yosuke Iwatani Mizuki Kyoda Hirohiko Nokiba Nobuyuki Amemiya Kosaku Nitta Ken Tsuchiya Late-Onset Neutropenia after Rituximab Treatment for Adult-Onset Nephrotic Syndrome Case Reports in Nephrology |
| title | Late-Onset Neutropenia after Rituximab Treatment for Adult-Onset Nephrotic Syndrome |
| title_full | Late-Onset Neutropenia after Rituximab Treatment for Adult-Onset Nephrotic Syndrome |
| title_fullStr | Late-Onset Neutropenia after Rituximab Treatment for Adult-Onset Nephrotic Syndrome |
| title_full_unstemmed | Late-Onset Neutropenia after Rituximab Treatment for Adult-Onset Nephrotic Syndrome |
| title_short | Late-Onset Neutropenia after Rituximab Treatment for Adult-Onset Nephrotic Syndrome |
| title_sort | late onset neutropenia after rituximab treatment for adult onset nephrotic syndrome |
| url | http://dx.doi.org/10.1155/2019/3580941 |
| work_keys_str_mv | AT mayukoyamazaki lateonsetneutropeniaafterrituximabtreatmentforadultonsetnephroticsyndrome AT hidekazusugiura lateonsetneutropeniaafterrituximabtreatmentforadultonsetnephroticsyndrome AT yosukeiwatani lateonsetneutropeniaafterrituximabtreatmentforadultonsetnephroticsyndrome AT mizukikyoda lateonsetneutropeniaafterrituximabtreatmentforadultonsetnephroticsyndrome AT hirohikonokiba lateonsetneutropeniaafterrituximabtreatmentforadultonsetnephroticsyndrome AT nobuyukiamemiya lateonsetneutropeniaafterrituximabtreatmentforadultonsetnephroticsyndrome AT kosakunitta lateonsetneutropeniaafterrituximabtreatmentforadultonsetnephroticsyndrome AT kentsuchiya lateonsetneutropeniaafterrituximabtreatmentforadultonsetnephroticsyndrome |