Stability of 3', 5'-o-(tetraisopropyldisiloxane-1,3-diyl)nucleosides in the presence of lewis acids

Trimethylsilyl trifluoromethanesulfonate catalyzes effective isomerization of 3',5'-O-(tetraisopropyldisiloxane1,3-diyl,TIPDS)nucleosides in 1,2-dicloroethane at 0C into 2',3'-O-TIPDS-derivatives to give 55-90% yields. On the other hand 3',5'-O-TIPDS-nucleosides except...

Full description

Saved in:

Bibliographic Details
Main Authors:	I. V. Kulikova, D. A. Muradova, S. N. Mikhailov
Format:	Article
Language:	Russian
Published:	MIREA - Russian Technological University 2008-10-01
Series:	Тонкие химические технологии
Subjects:	защитные группы нуклеозидов, изомеризация, 3′,5′-o-(тетраизопропилдисилоксан-1,3-диил)нуклеозиды, триметилсилилтрифторметан-сульфонат.
Online Access:	https://www.finechem-mirea.ru/jour/article/view/1538
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!

Stability of 3', 5'-o-(tetraisopropyldisiloxane-1,3-diyl)nucleosides in the presence of lewis acids

Similar Items