A dedicated skin-to-brain circuit for cool sensation in mice

A dedicated skin-to-brain circuit for cool sensation in mice

Abstract Perception of external temperature is essential for maintaining homeostasis and avoiding thermal injury. Although molecular thermosensors such as transient receptor potential melastatin type 8 (TRPM8) have been identified, the neural circuits responsible for transmitting cool signals remain...

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Bibliographic Details
Main Authors: Hankyu Lee, Chia Chun Hor, Lorraine R. Horwitz, Ailin Xiong, Xin-Yu Su, Daniel R. Soden, Sarah Yang, Wei Cai, Wenwen Zhang, Chen Li, Christopher Radcliff, Abbey Dinh, Tin Long Rex Fung, Ilma Rovcanin, Kevin P. Pipe, X. Z. Shawn Xu, Bo Duan
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61562-y
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