Modified Peroral Endoscopic Myotomy Technique for Type II Achalasia: A Multicenter Retrospective Study
Aim. This retrospective study is aimed at evaluating the outcomes of a modified peroral endoscopic myotomy (POEM) technique in patients with type II achalasia. Methods. We performed a modified POEM procedure, which involved a shorter (total myotomy length=4 cm), full-thickness myotomy, on 31 patient...
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| Format: | Article |
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Wiley
2022-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2022/3424470 |
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| author | Huahui Zhang Kuangjing Wang Ying Fang Zhe Xiong Min Lin Lifeng Jiang Qiuya Niu Jin Huang |
| author_facet | Huahui Zhang Kuangjing Wang Ying Fang Zhe Xiong Min Lin Lifeng Jiang Qiuya Niu Jin Huang |
| author_sort | Huahui Zhang |
| collection | DOAJ |
| description | Aim. This retrospective study is aimed at evaluating the outcomes of a modified peroral endoscopic myotomy (POEM) technique in patients with type II achalasia. Methods. We performed a modified POEM procedure, which involved a shorter (total myotomy length=4 cm), full-thickness myotomy, on 31 patients with type II achalasia. Clinical success rates, technical success rates, pre- and postoperative esophageal manometry results, complications, and reflux-related adverse events were evaluated. Results. The clinical success (Eckardt score≤3) rates were 100% and 88.9% within 2 years and beyond 2 years postoperatively, respectively. The median lower esophageal sphincter pressures (LESP) decreased from 31.6 (26.7-49.7) mmHg preoperatively to 13.4 (10.5-21.6) and 11.8 (7.4-16.7) mmHg (P<0.001) at 6 and 12 months postoperatively, respectively. The median integrated relaxation pressure (IRP) decreased from 27.8 (20.6-37.5) mmHg preoperatively to 12.9 (11.3-23.4) and 11.6 (9.6-16.8) mmHg (P<0.001) at 6 and 12 months after POEM, respectively. Only one case (3.2%) of mucosal injury, four (12.9%) cases of reflux esophagitis, and two (6.5%) cases of gastroesophageal reflux symptoms were reported. Conclusions. The modified POEM technique showed excellent outcomes in patients with type II achalasia. |
| format | Article |
| id | doaj-art-1f50350645af4b25b1955eba730e98e8 |
| institution | Kabale University |
| issn | 1687-630X |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
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| series | Gastroenterology Research and Practice |
| spelling | doaj-art-1f50350645af4b25b1955eba730e98e82025-02-03T05:59:38ZengWileyGastroenterology Research and Practice1687-630X2022-01-01202210.1155/2022/3424470Modified Peroral Endoscopic Myotomy Technique for Type II Achalasia: A Multicenter Retrospective StudyHuahui Zhang0Kuangjing Wang1Ying Fang2Zhe Xiong3Min Lin4Lifeng Jiang5Qiuya Niu6Jin Huang7Graduate School of Dalian Medical UniversityDepartment of GastroenterologyGraduate School of Dalian Medical UniversityGraduate School of Dalian Medical UniversityDepartment of GastroenterologyDepartment of GastroenterologyDepartment of GastroenterologyDepartment of GastroenterologyAim. This retrospective study is aimed at evaluating the outcomes of a modified peroral endoscopic myotomy (POEM) technique in patients with type II achalasia. Methods. We performed a modified POEM procedure, which involved a shorter (total myotomy length=4 cm), full-thickness myotomy, on 31 patients with type II achalasia. Clinical success rates, technical success rates, pre- and postoperative esophageal manometry results, complications, and reflux-related adverse events were evaluated. Results. The clinical success (Eckardt score≤3) rates were 100% and 88.9% within 2 years and beyond 2 years postoperatively, respectively. The median lower esophageal sphincter pressures (LESP) decreased from 31.6 (26.7-49.7) mmHg preoperatively to 13.4 (10.5-21.6) and 11.8 (7.4-16.7) mmHg (P<0.001) at 6 and 12 months postoperatively, respectively. The median integrated relaxation pressure (IRP) decreased from 27.8 (20.6-37.5) mmHg preoperatively to 12.9 (11.3-23.4) and 11.6 (9.6-16.8) mmHg (P<0.001) at 6 and 12 months after POEM, respectively. Only one case (3.2%) of mucosal injury, four (12.9%) cases of reflux esophagitis, and two (6.5%) cases of gastroesophageal reflux symptoms were reported. Conclusions. The modified POEM technique showed excellent outcomes in patients with type II achalasia.http://dx.doi.org/10.1155/2022/3424470 |
| spellingShingle | Huahui Zhang Kuangjing Wang Ying Fang Zhe Xiong Min Lin Lifeng Jiang Qiuya Niu Jin Huang Modified Peroral Endoscopic Myotomy Technique for Type II Achalasia: A Multicenter Retrospective Study Gastroenterology Research and Practice |
| title | Modified Peroral Endoscopic Myotomy Technique for Type II Achalasia: A Multicenter Retrospective Study |
| title_full | Modified Peroral Endoscopic Myotomy Technique for Type II Achalasia: A Multicenter Retrospective Study |
| title_fullStr | Modified Peroral Endoscopic Myotomy Technique for Type II Achalasia: A Multicenter Retrospective Study |
| title_full_unstemmed | Modified Peroral Endoscopic Myotomy Technique for Type II Achalasia: A Multicenter Retrospective Study |
| title_short | Modified Peroral Endoscopic Myotomy Technique for Type II Achalasia: A Multicenter Retrospective Study |
| title_sort | modified peroral endoscopic myotomy technique for type ii achalasia a multicenter retrospective study |
| url | http://dx.doi.org/10.1155/2022/3424470 |
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