Nonislet Cell Tumor Hypoglycemia in a Patient with Adrenal Cortical Carcinoma
Nonislet cell tumor hypoglycemia (NICTH) is a rare but serious paraneoplastic syndrome in which a tumor secretes incompletely processed precursors of insulin-like growth factor-II (IGF-II), causing hypoglycemia. Here, we report an exceptional case of NICTH caused by nonfunctioning adrenocortical car...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2016/5731417 |
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| author | Se Won Kim Seung-Eun Lee Young Lyun Oh Seokhwi Kim Sun Hee Park Jae Hyeon Kim |
| author_facet | Se Won Kim Seung-Eun Lee Young Lyun Oh Seokhwi Kim Sun Hee Park Jae Hyeon Kim |
| author_sort | Se Won Kim |
| collection | DOAJ |
| description | Nonislet cell tumor hypoglycemia (NICTH) is a rare but serious paraneoplastic syndrome in which a tumor secretes incompletely processed precursors of insulin-like growth factor-II (IGF-II), causing hypoglycemia. Here, we report an exceptional case of NICTH caused by nonfunctioning adrenocortical carcinoma in a 39-year-old male with recurrent hypoglycemia. The patient’s serum IGF-II/IGF-I ratio had increased to 27.8. The serum level of the IGF-II/IGF-I ratio was normalized after removal of the tumor, and the hypoglycemic attacks no longer occurred after the operation. |
| format | Article |
| id | doaj-art-1f412fd9f372405d82f24c8518c31214 |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-1f412fd9f372405d82f24c8518c312142025-02-03T06:01:31ZengWileyCase Reports in Endocrinology2090-65012090-651X2016-01-01201610.1155/2016/57314175731417Nonislet Cell Tumor Hypoglycemia in a Patient with Adrenal Cortical CarcinomaSe Won Kim0Seung-Eun Lee1Young Lyun Oh2Seokhwi Kim3Sun Hee Park4Jae Hyeon Kim5Division of Endocrinology, Department of Internal Medicine, Sahmyook Medical Center, Seoul, Republic of KoreaDepartment of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of KoreaDepartment of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of KoreaGraduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of KoreaDivision of Endocrinology, Department of Internal Medicine, Sahmyook Medical Center, Seoul, Republic of KoreaDepartment of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of KoreaNonislet cell tumor hypoglycemia (NICTH) is a rare but serious paraneoplastic syndrome in which a tumor secretes incompletely processed precursors of insulin-like growth factor-II (IGF-II), causing hypoglycemia. Here, we report an exceptional case of NICTH caused by nonfunctioning adrenocortical carcinoma in a 39-year-old male with recurrent hypoglycemia. The patient’s serum IGF-II/IGF-I ratio had increased to 27.8. The serum level of the IGF-II/IGF-I ratio was normalized after removal of the tumor, and the hypoglycemic attacks no longer occurred after the operation.http://dx.doi.org/10.1155/2016/5731417 |
| spellingShingle | Se Won Kim Seung-Eun Lee Young Lyun Oh Seokhwi Kim Sun Hee Park Jae Hyeon Kim Nonislet Cell Tumor Hypoglycemia in a Patient with Adrenal Cortical Carcinoma Case Reports in Endocrinology |
| title | Nonislet Cell Tumor Hypoglycemia in a Patient with Adrenal Cortical Carcinoma |
| title_full | Nonislet Cell Tumor Hypoglycemia in a Patient with Adrenal Cortical Carcinoma |
| title_fullStr | Nonislet Cell Tumor Hypoglycemia in a Patient with Adrenal Cortical Carcinoma |
| title_full_unstemmed | Nonislet Cell Tumor Hypoglycemia in a Patient with Adrenal Cortical Carcinoma |
| title_short | Nonislet Cell Tumor Hypoglycemia in a Patient with Adrenal Cortical Carcinoma |
| title_sort | nonislet cell tumor hypoglycemia in a patient with adrenal cortical carcinoma |
| url | http://dx.doi.org/10.1155/2016/5731417 |
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