Macrophage Extracellular Traps: Current Opinions and the State of Research regarding Various Diseases
Macrophages are an important component of the human immune system and play a key role in the immune response, which can protect the body against infection and regulate the development of tissue inflammation. Some studies found that macrophages can produce extracellular traps (ETs) under various cond...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2022/7050807 |
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| _version_ | 1832559124758396928 |
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| author | Weizhen Weng Zuoyu Hu Yunfeng Pan |
| author_facet | Weizhen Weng Zuoyu Hu Yunfeng Pan |
| author_sort | Weizhen Weng |
| collection | DOAJ |
| description | Macrophages are an important component of the human immune system and play a key role in the immune response, which can protect the body against infection and regulate the development of tissue inflammation. Some studies found that macrophages can produce extracellular traps (ETs) under various conditions of stimulation. ETs are web-like structures that consist of proteins and DNA. ETs are thought to immobilize and kill microorganisms, as well as play an important role in tissue damage, inflammatory progression, and autoimmune diseases. In this review, the structure, identification, mechanism, and research progress of macrophage extracellular traps (METs) in related diseases are reviewed. |
| format | Article |
| id | doaj-art-1f27bf5b6a41499886d1bb1811e5a318 |
| institution | Kabale University |
| issn | 2314-7156 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-1f27bf5b6a41499886d1bb1811e5a3182025-02-03T01:30:39ZengWileyJournal of Immunology Research2314-71562022-01-01202210.1155/2022/7050807Macrophage Extracellular Traps: Current Opinions and the State of Research regarding Various DiseasesWeizhen Weng0Zuoyu Hu1Yunfeng Pan2Division of RheumatologyDivision of RheumatologyDivision of RheumatologyMacrophages are an important component of the human immune system and play a key role in the immune response, which can protect the body against infection and regulate the development of tissue inflammation. Some studies found that macrophages can produce extracellular traps (ETs) under various conditions of stimulation. ETs are web-like structures that consist of proteins and DNA. ETs are thought to immobilize and kill microorganisms, as well as play an important role in tissue damage, inflammatory progression, and autoimmune diseases. In this review, the structure, identification, mechanism, and research progress of macrophage extracellular traps (METs) in related diseases are reviewed.http://dx.doi.org/10.1155/2022/7050807 |
| spellingShingle | Weizhen Weng Zuoyu Hu Yunfeng Pan Macrophage Extracellular Traps: Current Opinions and the State of Research regarding Various Diseases Journal of Immunology Research |
| title | Macrophage Extracellular Traps: Current Opinions and the State of Research regarding Various Diseases |
| title_full | Macrophage Extracellular Traps: Current Opinions and the State of Research regarding Various Diseases |
| title_fullStr | Macrophage Extracellular Traps: Current Opinions and the State of Research regarding Various Diseases |
| title_full_unstemmed | Macrophage Extracellular Traps: Current Opinions and the State of Research regarding Various Diseases |
| title_short | Macrophage Extracellular Traps: Current Opinions and the State of Research regarding Various Diseases |
| title_sort | macrophage extracellular traps current opinions and the state of research regarding various diseases |
| url | http://dx.doi.org/10.1155/2022/7050807 |
| work_keys_str_mv | AT weizhenweng macrophageextracellulartrapscurrentopinionsandthestateofresearchregardingvariousdiseases AT zuoyuhu macrophageextracellulartrapscurrentopinionsandthestateofresearchregardingvariousdiseases AT yunfengpan macrophageextracellulartrapscurrentopinionsandthestateofresearchregardingvariousdiseases |