SDF-1 alleviates osteoarthritis by resolving mitochondrial dysfunction through the activation of the Sirt3/PGC-1α signalling pathway
Abstract Objective Osteoarthritis (OA) is the most common form of joint disease. Currently, OA treatment is limited to controlling symptoms. Our previous study showed that stromal cell-derived factor 1 (SDF-1) delayed the progression of OA to a certain extent. The aim of this study was to explore th...
Saved in:
| Main Authors: | Yanping Zhao, Dan Lin, Xiaoying Zhu, Jingyao Yan, Yan Liang, Yanli Wang, Tianqi Dai, Zhiyi Zhang, Shuya Wang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-03-01
|
| Series: | Arthritis Research & Therapy |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13075-025-03509-8 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
SIRT1 antisense long noncoding RNA attenuates interleukin-1β-induced osteoarthritic gene expression in human chondrocytes through its mRNA interaction
by: Takeo Tokura, et al.
Published: (2025-07-01) -
NMN improves cardiac function in SIRT3 knockout mice via the SIRT1/PGC-1α pathway
by: Xiyao Zhao, et al.
Published: (2025-08-01) -
The protective role of omentin-1 in IL-1β-induced chondrocyte senescence
by: Bin Chai, et al.
Published: (2020-01-01) -
Surfactant protein D alleviates chondrocytes senescence by upregulating SIRT3/SOD2 pathway in osteoarthritis
by: Huanyu Jiang, et al.
Published: (2025-04-01) -
Association between mitochondrial SIRTs (SIRT3, SIRT4, and SIRT5) and PCOS
by: Liying Huang, et al.
Published: (2025-07-01)