Fine-mapping and initial characterization of QT interval loci in African Americans.

Fine-mapping and initial characterization of QT interval loci in African Americans.

The QT interval (QT) is heritable and its prolongation is a risk factor for ventricular tachyarrhythmias and sudden death. Most genetic studies of QT have examined European ancestral populations; however, the increased genetic diversity in African Americans provides opportunities to narrow associati...

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Main Authors: Christy L Avery, Praveen Sethupathy, Steven Buyske, Qianchuan He, Dan-Yu Lin, Dan E Arking, Cara L Carty, David Duggan, Megan D Fesinmeyer, Lucia A Hindorff, Janina M Jeff, Liviu Klein, Kristen K Patton, Ulrike Peters, Ralph V Shohet, Nona Sotoodehnia, Alicia M Young, Charles Kooperberg, Christopher A Haiman, Karen L Mohlke, Eric A Whitsel, Kari E North
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002870&type=printable
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