Toxoplasma gondii virulence factor ROP1 reduces parasite susceptibility to murine and human innate immune restriction.
Toxoplasma gondii is an intracellular parasite that can infect many host species and is a cause of significant human morbidity worldwide. T. gondii secretes a diverse array of effector proteins into the host cell which are critical for infection. The vast majority of these secreted proteins have no...
Saved in:
| Main Authors: | Simon Butterworth, Francesca Torelli, Eloise J Lockyer, Jeanette Wagener, Ok-Ryul Song, Malgorzata Broncel, Matt R G Russell, Aline Cristina A Moreira-Souza, Joanna C Young, Moritz Treeck |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2022-12-01
|
| Series: | PLoS Pathogens |
| Online Access: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011021&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
GRA12 is a common virulence factor across Toxoplasma gondii strains and mouse subspecies
by: Francesca Torelli, et al.
Published: (2025-04-01) -
A heterotrimeric complex of Toxoplasma proteins promotes parasite survival in interferon gamma-stimulated human cells.
by: Eloise J Lockyer, et al.
Published: (2023-07-01) -
The polymorphic pseudokinase ROP5 controls virulence in Toxoplasma gondii by regulating the active kinase ROP18.
by: Michael S Behnke, et al.
Published: (2012-01-01) -
Toxoplasma gondii virulence in mice is determined by the pseudokinase ROP5B and countered by an IRG-GBP protein interplay
by: Shishir Singh, et al.
Published: (2025-07-01) -
ROP18 is a rhoptry kinase controlling the intracellular proliferation of Toxoplasma gondii.
by: Hiba El Hajj, et al.
Published: (2007-02-01)