Evaluation of glucocorticoid receptor function in COPD lung macrophages using beclomethasone-17-monopropionate.

Evaluation of glucocorticoid receptor function in COPD lung macrophages using beclomethasone-17-monopropionate.

Previous studies of glucocorticoid receptor (GR) function in COPD lung macrophages have used dexamethasone to evaluate inhibition of cytokine production. We have now used the clinically relevant corticosteroid beclomethasone-17-monopropionate (17-BMP) to assess GR function in COPD lung macrophages,...

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Main Authors: Jonathan Plumb, Laura Robinson, Simon Lea, Antonia Banyard, John Blaikley, David Ray, Andrea Bizzi, Giorgina Volpi, Fabrizio Facchinetti, Dave Singh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0064257
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