Synthesis, Characterization and Biological Activities of 3,5-Diaryltetrahydro-N-[(phenylamino)methyl]-1,4-thiazine-1,1-dioxide

Synthesis of 3,5-diaryltetrahydro-N- [(4’-nitroanilino)methyl-thiazine-1,1-dioxide and N-[(4’-methylanilino)methyl-]-1,4-thiazine-1,1-dioxides by condensing 3,5-diaryl-tetrahydro-1,4-thiazine-1,1-dioxide with formaldehyde and 4-nitroaniline/4-methylaniline in the presence of hydrochloric acid is rep...

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Main Authors: V. Sundari, G. Nagarajan, S. Gurumurthy, R. Valliappan
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2009/254747
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author V. Sundari
G. Nagarajan
S. Gurumurthy
R. Valliappan
author_facet V. Sundari
G. Nagarajan
S. Gurumurthy
R. Valliappan
author_sort V. Sundari
collection DOAJ
description Synthesis of 3,5-diaryltetrahydro-N- [(4’-nitroanilino)methyl-thiazine-1,1-dioxide and N-[(4’-methylanilino)methyl-]-1,4-thiazine-1,1-dioxides by condensing 3,5-diaryl-tetrahydro-1,4-thiazine-1,1-dioxide with formaldehyde and 4-nitroaniline/4-methylaniline in the presence of hydrochloric acid is reported. The structures of the synthesized compounds have been confirmed by elemental and spectral analysis. The preliminary screening of the compounds for their biological activities gives significant results
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institution Kabale University
issn 0973-4945
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language English
publishDate 2009-01-01
publisher Wiley
record_format Article
series E-Journal of Chemistry
spelling doaj-art-1ec39490f06b44db86081cde37416f4f2025-02-03T06:48:39ZengWileyE-Journal of Chemistry0973-49452090-98102009-01-016117718210.1155/2009/254747Synthesis, Characterization and Biological Activities of 3,5-Diaryltetrahydro-N-[(phenylamino)methyl]-1,4-thiazine-1,1-dioxideV. Sundari0G. Nagarajan1S. Gurumurthy2R. Valliappan3Chemistry Division, Faculty of Engineering and Technology, Annamalai University, Annamalai Nagar-608 002, IndiaChemistry Division, Faculty of Engineering and Technology, Annamalai University, Annamalai Nagar-608 002, IndiaChemistry Division, Faculty of Engineering and Technology, Annamalai University, Annamalai Nagar-608 002, IndiaChemistry Wing, DDE, Annamalai University, Annamalai Nagar-608 002, IndiaSynthesis of 3,5-diaryltetrahydro-N- [(4’-nitroanilino)methyl-thiazine-1,1-dioxide and N-[(4’-methylanilino)methyl-]-1,4-thiazine-1,1-dioxides by condensing 3,5-diaryl-tetrahydro-1,4-thiazine-1,1-dioxide with formaldehyde and 4-nitroaniline/4-methylaniline in the presence of hydrochloric acid is reported. The structures of the synthesized compounds have been confirmed by elemental and spectral analysis. The preliminary screening of the compounds for their biological activities gives significant resultshttp://dx.doi.org/10.1155/2009/254747
spellingShingle V. Sundari
G. Nagarajan
S. Gurumurthy
R. Valliappan
Synthesis, Characterization and Biological Activities of 3,5-Diaryltetrahydro-N-[(phenylamino)methyl]-1,4-thiazine-1,1-dioxide
E-Journal of Chemistry
title Synthesis, Characterization and Biological Activities of 3,5-Diaryltetrahydro-N-[(phenylamino)methyl]-1,4-thiazine-1,1-dioxide
title_full Synthesis, Characterization and Biological Activities of 3,5-Diaryltetrahydro-N-[(phenylamino)methyl]-1,4-thiazine-1,1-dioxide
title_fullStr Synthesis, Characterization and Biological Activities of 3,5-Diaryltetrahydro-N-[(phenylamino)methyl]-1,4-thiazine-1,1-dioxide
title_full_unstemmed Synthesis, Characterization and Biological Activities of 3,5-Diaryltetrahydro-N-[(phenylamino)methyl]-1,4-thiazine-1,1-dioxide
title_short Synthesis, Characterization and Biological Activities of 3,5-Diaryltetrahydro-N-[(phenylamino)methyl]-1,4-thiazine-1,1-dioxide
title_sort synthesis characterization and biological activities of 3 5 diaryltetrahydro n phenylamino methyl 1 4 thiazine 1 1 dioxide
url http://dx.doi.org/10.1155/2009/254747
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