Noni Juice Improves Serum Lipid Profiles and Other Risk Markers in Cigarette Smokers
Cigarette smoke-induced oxidative stress leads to dyslipidemia and systemic inflammation. Morinda citrifolia (noni) fruit juice has been found previously to have a significant antioxidant activity. One hundred thirty-two adult heavy smokers completed a randomized, double blind, pl...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/2012/594657 |
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| author | Mian-Ying Wang Lin Peng Vicki Weidenbacher-Hoper Shixin Deng Gary Anderson Brett J. West |
| author_facet | Mian-Ying Wang Lin Peng Vicki Weidenbacher-Hoper Shixin Deng Gary Anderson Brett J. West |
| author_sort | Mian-Ying Wang |
| collection | DOAJ |
| description | Cigarette smoke-induced oxidative stress leads to dyslipidemia and systemic inflammation. Morinda citrifolia (noni) fruit juice has been found previously to
have a significant antioxidant activity. One hundred thirty-two adult heavy smokers completed a randomized, double blind, placebo-controlled clinical trial designed to investigate the effect of noni juice on serum cholesterol, triglyceride, low density lipoprotein cholesterol (LDL), high density lipoprotein cholesterol (HDL), high-sensitivity C-reactive protein (hs-CRP), and homocysteine. Volunteers drank noni juice or a fruit juice placebo daily for one month. Drinking 29.5 mL to 188 mL of noni juice per day significantly reduced cholesterol levels, triglycerides, and hs-CRP. Decreases in LDL and homocysteine, as well increases in HDL, were also observed among noni juice drinkers. The placebo, which was devoid of iridoid glycosides, did not significantly influence blood lipid profiles or hs-CRP. Noni juice was able to mitigate cigarette smoke-induced dyslipidemia, an activity associated with the presence of iridoids. |
| format | Article |
| id | doaj-art-1ec16b888df94402b2f444ea731ace32 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-1ec16b888df94402b2f444ea731ace322025-02-03T06:12:28ZengWileyThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/594657594657Noni Juice Improves Serum Lipid Profiles and Other Risk Markers in Cigarette SmokersMian-Ying Wang0Lin Peng1Vicki Weidenbacher-Hoper2Shixin Deng3Gary Anderson4Brett J. West5Department of Pathology, University of Illinois College of Medicine at Rockford, 1601 Parkview Avenue, Rockford, IL 61107, USADepartment of Pathology, University of Illinois College of Medicine at Rockford, 1601 Parkview Avenue, Rockford, IL 61107, USADepartment of Family and Community Medicine, University of Illinois College of Medicine at Rockford, 1601 Parkview Avenue, Rockford, IL 61107, USADepartment of Research and Development, Morinda Inc., 737 East 1180 South, American Fork, UT 84003, USADepartment of Pathology, University of Illinois College of Medicine at Rockford, 1601 Parkview Avenue, Rockford, IL 61107, USADepartment of Research and Development, Morinda Inc., 737 East 1180 South, American Fork, UT 84003, USACigarette smoke-induced oxidative stress leads to dyslipidemia and systemic inflammation. Morinda citrifolia (noni) fruit juice has been found previously to have a significant antioxidant activity. One hundred thirty-two adult heavy smokers completed a randomized, double blind, placebo-controlled clinical trial designed to investigate the effect of noni juice on serum cholesterol, triglyceride, low density lipoprotein cholesterol (LDL), high density lipoprotein cholesterol (HDL), high-sensitivity C-reactive protein (hs-CRP), and homocysteine. Volunteers drank noni juice or a fruit juice placebo daily for one month. Drinking 29.5 mL to 188 mL of noni juice per day significantly reduced cholesterol levels, triglycerides, and hs-CRP. Decreases in LDL and homocysteine, as well increases in HDL, were also observed among noni juice drinkers. The placebo, which was devoid of iridoid glycosides, did not significantly influence blood lipid profiles or hs-CRP. Noni juice was able to mitigate cigarette smoke-induced dyslipidemia, an activity associated with the presence of iridoids.http://dx.doi.org/10.1100/2012/594657 |
| spellingShingle | Mian-Ying Wang Lin Peng Vicki Weidenbacher-Hoper Shixin Deng Gary Anderson Brett J. West Noni Juice Improves Serum Lipid Profiles and Other Risk Markers in Cigarette Smokers The Scientific World Journal |
| title | Noni Juice Improves Serum Lipid Profiles and Other Risk Markers in Cigarette Smokers |
| title_full | Noni Juice Improves Serum Lipid Profiles and Other Risk Markers in Cigarette Smokers |
| title_fullStr | Noni Juice Improves Serum Lipid Profiles and Other Risk Markers in Cigarette Smokers |
| title_full_unstemmed | Noni Juice Improves Serum Lipid Profiles and Other Risk Markers in Cigarette Smokers |
| title_short | Noni Juice Improves Serum Lipid Profiles and Other Risk Markers in Cigarette Smokers |
| title_sort | noni juice improves serum lipid profiles and other risk markers in cigarette smokers |
| url | http://dx.doi.org/10.1100/2012/594657 |
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