Multiple Symmetric Lipomatosis: A Review of 3 Cases

Multiple symmetrical lipomatosis, or Madelung's disease, is a rare disease of unknown etiology. It is characterized by the presence of loose adipose tissue deposits localized in the cervical region and in the upper body. The neoformations grow slowly and their initial consequence is purely esth...

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Main Authors: Emilio Mevio, Michele Sbrocca, Mauro Mullace, Silvia Viglione, Niccolò Mevio
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Otolaryngology
Online Access:http://dx.doi.org/10.1155/2012/910526
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author Emilio Mevio
Michele Sbrocca
Mauro Mullace
Silvia Viglione
Niccolò Mevio
author_facet Emilio Mevio
Michele Sbrocca
Mauro Mullace
Silvia Viglione
Niccolò Mevio
author_sort Emilio Mevio
collection DOAJ
description Multiple symmetrical lipomatosis, or Madelung's disease, is a rare disease of unknown etiology. It is characterized by the presence of loose adipose tissue deposits localized in the cervical region and in the upper body. The neoformations grow slowly and their initial consequence is purely esthetic. They can, however, lead to compression of the laryngotacheal area and of the esophagus. This disease usually affects middle-aged males from the Mediterranean area with a history of alcohol abuse. Although most cases have been sporadic, a few authors have indicated that the disorder may be hereditary. It is thought that this pathology originates from an alteration in lipid metabolism. Since the patients were asymptomatic temperance and diet was proposed, surgical removal of the lipomatose mass is the treatment of choice in case of complications due to fat mass compression on upper aerodigestive tract. The authors present three cases of Madelung's disease with different and particular manifestations.
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spelling doaj-art-1ebd7cf6b7ff48de9f39f14a906fe0be2025-02-03T01:21:08ZengWileyCase Reports in Otolaryngology2090-67652090-67732012-01-01201210.1155/2012/910526910526Multiple Symmetric Lipomatosis: A Review of 3 CasesEmilio Mevio0Michele Sbrocca1Mauro Mullace2Silvia Viglione3Niccolò Mevio4Department of Otorhinolaryngology, Ospedale Fornaroli, via Donatore del Sangue, 20013 Magenta, ItalyDepartment of Otorhinolaryngology, Ospedale Fornaroli, via Donatore del Sangue, 20013 Magenta, ItalyDepartment of Otorhinolaryngology, Ospedale Fornaroli, via Donatore del Sangue, 20013 Magenta, ItalyDepartment of Otorhinolaryngology, Ospedale Fornaroli, via Donatore del Sangue, 20013 Magenta, ItalyDepartment of Otorhinolaryngology, Ospedale Fornaroli, via Donatore del Sangue, 20013 Magenta, ItalyMultiple symmetrical lipomatosis, or Madelung's disease, is a rare disease of unknown etiology. It is characterized by the presence of loose adipose tissue deposits localized in the cervical region and in the upper body. The neoformations grow slowly and their initial consequence is purely esthetic. They can, however, lead to compression of the laryngotacheal area and of the esophagus. This disease usually affects middle-aged males from the Mediterranean area with a history of alcohol abuse. Although most cases have been sporadic, a few authors have indicated that the disorder may be hereditary. It is thought that this pathology originates from an alteration in lipid metabolism. Since the patients were asymptomatic temperance and diet was proposed, surgical removal of the lipomatose mass is the treatment of choice in case of complications due to fat mass compression on upper aerodigestive tract. The authors present three cases of Madelung's disease with different and particular manifestations.http://dx.doi.org/10.1155/2012/910526
spellingShingle Emilio Mevio
Michele Sbrocca
Mauro Mullace
Silvia Viglione
Niccolò Mevio
Multiple Symmetric Lipomatosis: A Review of 3 Cases
Case Reports in Otolaryngology
title Multiple Symmetric Lipomatosis: A Review of 3 Cases
title_full Multiple Symmetric Lipomatosis: A Review of 3 Cases
title_fullStr Multiple Symmetric Lipomatosis: A Review of 3 Cases
title_full_unstemmed Multiple Symmetric Lipomatosis: A Review of 3 Cases
title_short Multiple Symmetric Lipomatosis: A Review of 3 Cases
title_sort multiple symmetric lipomatosis a review of 3 cases
url http://dx.doi.org/10.1155/2012/910526
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