A Case of Recurrent Cryptococcal Meningoencephalitis in an Immunocompetent Female
Cryptococcus neoformans is commonly associated with meningoencephalitis in immunocompromised patients and occasionally in apparently healthy individuals. Duration and regimen of antifungal treatment vary depending on the nature of the host and extent of disease and CNS shunts are placed in persisten...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2014/407348 |
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| author | Negin Niknam Negar Niknam Kola Dushaj Erfidia Restrepo |
| author_facet | Negin Niknam Negar Niknam Kola Dushaj Erfidia Restrepo |
| author_sort | Negin Niknam |
| collection | DOAJ |
| description | Cryptococcus neoformans is commonly associated with meningoencephalitis in immunocompromised patients and occasionally in apparently healthy individuals. Duration and regimen of antifungal treatment vary depending on the nature of the host and extent of disease and CNS shunts are placed in persistently elevated intracranial pressures. Recurrence of infection after initial treatment is not uncommon in HIV positive patients, Kaya et al. (2012) and Illnait-zaragozí et al. (2010). We describe a 39-year-old immunocompetent female that presented with neurologic deficits and increased intracranial pressure (ICP) due to cryptococcal meningoencephalitis that had a complicated course with drug induced hepatitis and persistently increased ICP that ultimately required shunt placement and presented again with relapse of cryptococcal meningoencephalitis after completion of antifungal treatment. Our case shows that recurrent cryptococcal meningitis can be seen in immunocompetent patients due to prolonged placement of CNS shunt and suggests that shunts should be removed after resolution of meningitis. |
| format | Article |
| id | doaj-art-1e8b41c82cb645c5b2cd86f8ea7c43b4 |
| institution | Kabale University |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-1e8b41c82cb645c5b2cd86f8ea7c43b42025-02-03T01:29:12ZengWileyCase Reports in Infectious Diseases2090-66252090-66332014-01-01201410.1155/2014/407348407348A Case of Recurrent Cryptococcal Meningoencephalitis in an Immunocompetent FemaleNegin Niknam0Negar Niknam1Kola Dushaj2Erfidia Restrepo3Department of Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, Jamaica, NY 11432, USADepartment of Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, Jamaica, NY 11432, USADepartment of Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, Jamaica, NY 11432, USADepartment of Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, Jamaica, NY 11432, USACryptococcus neoformans is commonly associated with meningoencephalitis in immunocompromised patients and occasionally in apparently healthy individuals. Duration and regimen of antifungal treatment vary depending on the nature of the host and extent of disease and CNS shunts are placed in persistently elevated intracranial pressures. Recurrence of infection after initial treatment is not uncommon in HIV positive patients, Kaya et al. (2012) and Illnait-zaragozí et al. (2010). We describe a 39-year-old immunocompetent female that presented with neurologic deficits and increased intracranial pressure (ICP) due to cryptococcal meningoencephalitis that had a complicated course with drug induced hepatitis and persistently increased ICP that ultimately required shunt placement and presented again with relapse of cryptococcal meningoencephalitis after completion of antifungal treatment. Our case shows that recurrent cryptococcal meningitis can be seen in immunocompetent patients due to prolonged placement of CNS shunt and suggests that shunts should be removed after resolution of meningitis.http://dx.doi.org/10.1155/2014/407348 |
| spellingShingle | Negin Niknam Negar Niknam Kola Dushaj Erfidia Restrepo A Case of Recurrent Cryptococcal Meningoencephalitis in an Immunocompetent Female Case Reports in Infectious Diseases |
| title | A Case of Recurrent Cryptococcal Meningoencephalitis in an Immunocompetent Female |
| title_full | A Case of Recurrent Cryptococcal Meningoencephalitis in an Immunocompetent Female |
| title_fullStr | A Case of Recurrent Cryptococcal Meningoencephalitis in an Immunocompetent Female |
| title_full_unstemmed | A Case of Recurrent Cryptococcal Meningoencephalitis in an Immunocompetent Female |
| title_short | A Case of Recurrent Cryptococcal Meningoencephalitis in an Immunocompetent Female |
| title_sort | case of recurrent cryptococcal meningoencephalitis in an immunocompetent female |
| url | http://dx.doi.org/10.1155/2014/407348 |
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