Role of fructose in renal cell carcinoma progression

Role of fructose in renal cell carcinoma progression

Abstract Renal cell carcinoma (RCC) is a highly malignant tumor with a poor prognosis, underscoring the urgent need for novel therapeutic strategies. RCC cells exhibit rapid proliferation and high metabolic demands, leading to hypoglycemic and hypoxic conditions within the tumor microenvironment (TM...

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Bibliographic Details
Main Authors: Jixuan Miao, Di Wang, Ruochong Pang, Hao Zhang, Yuyun Wu, Xingwei Sun, Yong Jin
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Oncology
Subjects:
Renal cell carcinoma
Fructose
Tumor microenvironment
CAMP/PKA signaling pathway
Tumor progression
Online Access:https://doi.org/10.1007/s12672-025-02688-9
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