Unusual Relapse of Primary Central Nervous System Lymphoma at Site of Lumbar Puncture

Primary CNS lymphoma (PCNSL) is a rare non-Hodgkin’s lymphoma confined to the CNS. Local relapse of this disease is common, but extracranial or subcutaneous metastasis is rare with only a few cases being reported in literature. We report a 63-year-old male patient, who responded well to treatment fo...

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Main Authors: Zartaj Ahmed, Ramesh K. Ramanathan, Sunil Ram, James Newell, Maqbool Halepota
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2014/161952
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author Zartaj Ahmed
Ramesh K. Ramanathan
Sunil Ram
James Newell
Maqbool Halepota
author_facet Zartaj Ahmed
Ramesh K. Ramanathan
Sunil Ram
James Newell
Maqbool Halepota
author_sort Zartaj Ahmed
collection DOAJ
description Primary CNS lymphoma (PCNSL) is a rare non-Hodgkin’s lymphoma confined to the CNS. Local relapse of this disease is common, but extracranial or subcutaneous metastasis is rare with only a few cases being reported in literature. We report a 63-year-old male patient, who responded well to treatment for PCNSL but relapsed two and half years later with a lumbosacral nodule at the site of a previous lumbar puncture due to microscopic tumor seeding. Clinicians treating patients with PCNSL must remain alert to the possibility of extracranial solitary relapse even after the resolution of initial disease because prompt treatment can result in a good outcome.
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institution Kabale University
issn 2090-6560
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publisher Wiley
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series Case Reports in Hematology
spelling doaj-art-1e7ba9e7ceec44558fb14531584d99042025-02-03T05:58:25ZengWileyCase Reports in Hematology2090-65602090-65792014-01-01201410.1155/2014/161952161952Unusual Relapse of Primary Central Nervous System Lymphoma at Site of Lumbar PunctureZartaj Ahmed0Ramesh K. Ramanathan1Sunil Ram2James Newell3Maqbool Halepota4Dow Medical College, Dow University of Health Sciences, Baba-e-Urdu Road, Karachi 74200, PakistanVirginia G Piper Cancer Centre, 10460 N. 92nd Street, Suite No. 200, Scottsdale, AZ 85258, USAScottsdale Medical Imaging, 3501 N. Scottsdale Road No. 130, Scottsdale, AZ 85251, USAScottsdale Pathology Associates, 9003 E. Shea Boulevard, Scottsdale, AZ 85260, USAPalo Verde Cancer Centre, 10460 N. 92nd Street, Suite 402, Scottsdale, AZ 85258, USAPrimary CNS lymphoma (PCNSL) is a rare non-Hodgkin’s lymphoma confined to the CNS. Local relapse of this disease is common, but extracranial or subcutaneous metastasis is rare with only a few cases being reported in literature. We report a 63-year-old male patient, who responded well to treatment for PCNSL but relapsed two and half years later with a lumbosacral nodule at the site of a previous lumbar puncture due to microscopic tumor seeding. Clinicians treating patients with PCNSL must remain alert to the possibility of extracranial solitary relapse even after the resolution of initial disease because prompt treatment can result in a good outcome.http://dx.doi.org/10.1155/2014/161952
spellingShingle Zartaj Ahmed
Ramesh K. Ramanathan
Sunil Ram
James Newell
Maqbool Halepota
Unusual Relapse of Primary Central Nervous System Lymphoma at Site of Lumbar Puncture
Case Reports in Hematology
title Unusual Relapse of Primary Central Nervous System Lymphoma at Site of Lumbar Puncture
title_full Unusual Relapse of Primary Central Nervous System Lymphoma at Site of Lumbar Puncture
title_fullStr Unusual Relapse of Primary Central Nervous System Lymphoma at Site of Lumbar Puncture
title_full_unstemmed Unusual Relapse of Primary Central Nervous System Lymphoma at Site of Lumbar Puncture
title_short Unusual Relapse of Primary Central Nervous System Lymphoma at Site of Lumbar Puncture
title_sort unusual relapse of primary central nervous system lymphoma at site of lumbar puncture
url http://dx.doi.org/10.1155/2014/161952
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