An in vitro model that recapitulates the epithelial to mesenchymal transition (EMT) in human breast cancer.

The epithelial to mesenchymal transition (EMT) is a developmental program in which epithelial cells down-regulate their cell-cell junctions, acquire spindle cell morphology and exhibit cellular motility. In human breast cancer, invasion into surrounding tissue is the first step in metastatic progres...

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Bibliographic Details
Main Authors: Elad Katz, Sylvie Dubois-Marshall, Andrew H Sims, Philippe Gautier, Helen Caldwell, Richard R Meehan, David J Harrison
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0017083&type=printable
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