Unusual Presentation of a Small-Cell Variant of Anaplastic Large-Cell Lymphoma Case: When a Septic Picture Is Not Sepsis

We report a case of a small-cell variant of anaplastic large-cell lymphoma, with an unusual clinical presentation mimicking sepsis and a fulminant clinic course, in a 48-year-old Caucasian female. In this report, we discuss the diagnostic challenge, histopathologic features, and unique cytogenetic f...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhou Yu, Yifan Pang, Linda Wang, Daniel E. Ezekwudo, Foluso Ogunleye, Susanna S. Gaikazian, Mark Micale, James Huang, Ann Marie Blenc, Ishmael Jaiyesimi
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2017/7292148
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832563829050966016
author Zhou Yu
Yifan Pang
Linda Wang
Daniel E. Ezekwudo
Foluso Ogunleye
Susanna S. Gaikazian
Mark Micale
James Huang
Ann Marie Blenc
Ishmael Jaiyesimi
author_facet Zhou Yu
Yifan Pang
Linda Wang
Daniel E. Ezekwudo
Foluso Ogunleye
Susanna S. Gaikazian
Mark Micale
James Huang
Ann Marie Blenc
Ishmael Jaiyesimi
author_sort Zhou Yu
collection DOAJ
description We report a case of a small-cell variant of anaplastic large-cell lymphoma, with an unusual clinical presentation mimicking sepsis and a fulminant clinic course, in a 48-year-old Caucasian female. In this report, we discuss the diagnostic challenge, histopathologic features, and unique cytogenetic features of this case, in order to raise awareness of this rare presentation and emphasize the importance of meticulous peripheral smear examination and early bone marrow evaluation.
format Article
id doaj-art-1e6d8396667640c690425c6242762aa7
institution Kabale University
issn 2090-6560
2090-6579
language English
publishDate 2017-01-01
publisher Wiley
record_format Article
series Case Reports in Hematology
spelling doaj-art-1e6d8396667640c690425c6242762aa72025-02-03T01:12:26ZengWileyCase Reports in Hematology2090-65602090-65792017-01-01201710.1155/2017/72921487292148Unusual Presentation of a Small-Cell Variant of Anaplastic Large-Cell Lymphoma Case: When a Septic Picture Is Not SepsisZhou Yu0Yifan Pang1Linda Wang2Daniel E. Ezekwudo3Foluso Ogunleye4Susanna S. Gaikazian5Mark Micale6James Huang7Ann Marie Blenc8Ishmael Jaiyesimi9Department of Hematology and Oncology, William Beaumont Hospital, Royal Oak, MI, USAOakland University William Beaumont School of Medicine, Rochester, MI, USAOakland University William Beaumont School of Medicine, Rochester, MI, USADepartment of Hematology and Oncology, William Beaumont Hospital, Royal Oak, MI, USADepartment of Hematology and Oncology, William Beaumont Hospital, Royal Oak, MI, USADepartment of Hematology and Oncology, William Beaumont Hospital, Royal Oak, MI, USAOakland University William Beaumont School of Medicine, Rochester, MI, USAOakland University William Beaumont School of Medicine, Rochester, MI, USAOakland University William Beaumont School of Medicine, Rochester, MI, USADepartment of Hematology and Oncology, William Beaumont Hospital, Royal Oak, MI, USAWe report a case of a small-cell variant of anaplastic large-cell lymphoma, with an unusual clinical presentation mimicking sepsis and a fulminant clinic course, in a 48-year-old Caucasian female. In this report, we discuss the diagnostic challenge, histopathologic features, and unique cytogenetic features of this case, in order to raise awareness of this rare presentation and emphasize the importance of meticulous peripheral smear examination and early bone marrow evaluation.http://dx.doi.org/10.1155/2017/7292148
spellingShingle Zhou Yu
Yifan Pang
Linda Wang
Daniel E. Ezekwudo
Foluso Ogunleye
Susanna S. Gaikazian
Mark Micale
James Huang
Ann Marie Blenc
Ishmael Jaiyesimi
Unusual Presentation of a Small-Cell Variant of Anaplastic Large-Cell Lymphoma Case: When a Septic Picture Is Not Sepsis
Case Reports in Hematology
title Unusual Presentation of a Small-Cell Variant of Anaplastic Large-Cell Lymphoma Case: When a Septic Picture Is Not Sepsis
title_full Unusual Presentation of a Small-Cell Variant of Anaplastic Large-Cell Lymphoma Case: When a Septic Picture Is Not Sepsis
title_fullStr Unusual Presentation of a Small-Cell Variant of Anaplastic Large-Cell Lymphoma Case: When a Septic Picture Is Not Sepsis
title_full_unstemmed Unusual Presentation of a Small-Cell Variant of Anaplastic Large-Cell Lymphoma Case: When a Septic Picture Is Not Sepsis
title_short Unusual Presentation of a Small-Cell Variant of Anaplastic Large-Cell Lymphoma Case: When a Septic Picture Is Not Sepsis
title_sort unusual presentation of a small cell variant of anaplastic large cell lymphoma case when a septic picture is not sepsis
url http://dx.doi.org/10.1155/2017/7292148
work_keys_str_mv AT zhouyu unusualpresentationofasmallcellvariantofanaplasticlargecelllymphomacasewhenasepticpictureisnotsepsis
AT yifanpang unusualpresentationofasmallcellvariantofanaplasticlargecelllymphomacasewhenasepticpictureisnotsepsis
AT lindawang unusualpresentationofasmallcellvariantofanaplasticlargecelllymphomacasewhenasepticpictureisnotsepsis
AT danieleezekwudo unusualpresentationofasmallcellvariantofanaplasticlargecelllymphomacasewhenasepticpictureisnotsepsis
AT folusoogunleye unusualpresentationofasmallcellvariantofanaplasticlargecelllymphomacasewhenasepticpictureisnotsepsis
AT susannasgaikazian unusualpresentationofasmallcellvariantofanaplasticlargecelllymphomacasewhenasepticpictureisnotsepsis
AT markmicale unusualpresentationofasmallcellvariantofanaplasticlargecelllymphomacasewhenasepticpictureisnotsepsis
AT jameshuang unusualpresentationofasmallcellvariantofanaplasticlargecelllymphomacasewhenasepticpictureisnotsepsis
AT annmarieblenc unusualpresentationofasmallcellvariantofanaplasticlargecelllymphomacasewhenasepticpictureisnotsepsis
AT ishmaeljaiyesimi unusualpresentationofasmallcellvariantofanaplasticlargecelllymphomacasewhenasepticpictureisnotsepsis